C₁₁H₁₁FO₂

Base Information

Chemical Name:C₁₁H₁₁FO₂
CAS No.:1402585-81-2
Molecular Formula:C₁₁H₁₁FO₂
Molecular Weight:194.206
Hs Code.:

C<sub>11</sub>H<sub>11</sub>FO<sub>2</sub>

Synonyms:C₁₁H₁₁FO₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₁H₁₁FO₂

Chemical Property:

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Technology Process of C₁₁H₁₁FO₂

There total 4 articles about C₁₁H₁₁FO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1402585-80-1
C₁₂H₁₃FO₂

: 1402585-81-2
C₁₁H₁₁FO₂

Guidance literature:: With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 23 ℃; for 2h;

Reference yield:

: 81937-33-9
2-(4-amino-3-fluorophenyl)propionic acid

: 1402585-81-2
C₁₁H₁₁FO₂

Guidance literature:: Multi-step reaction with 4 steps

1: thionyl chloride / 2 h / Cooling with ice

2: sodium nitrite; toluene-4-sulfonic acid; potassium iodide / water; acetonitrile / 10 - 20 °C

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride / N,N-dimethyl-formamide / 15 h / 23 °C / Inert atmosphere

4: lithium hydroxide monohydrate; water / tetrahydrofuran / 2 h / 23 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; thionyl chloride; lithium hydroxide monohydrate; water; toluene-4-sulfonic acid; potassium iodide; lithium chloride; sodium nitrite; In tetrahydrofuran; water; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 90500-55-3
(±)-methyl 2-(4-amino-3-fluorophenyl)propanoate

: 1402585-81-2
C₁₁H₁₁FO₂

Guidance literature:: Multi-step reaction with 3 steps

1: sodium nitrite; toluene-4-sulfonic acid; potassium iodide / water; acetonitrile / 10 - 20 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride / N,N-dimethyl-formamide / 15 h / 23 °C / Inert atmosphere

3: lithium hydroxide monohydrate; water / tetrahydrofuran / 2 h / 23 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium hydroxide monohydrate; water; toluene-4-sulfonic acid; potassium iodide; lithium chloride; sodium nitrite; In tetrahydrofuran; water; N,N-dimethyl-formamide; acetonitrile;