(2S)-piperidine-1,2-dicarboxylic acid 1-tert-butyl 2-<3'-(3,4,5-trimethoxyphenyl)propyl> diester

Base Information

Chemical Name:(2S)-piperidine-1,2-dicarboxylic acid 1-tert-butyl 2-<3'-(3,4,5-trimethoxyphenyl)propyl> diester
CAS No.:175721-87-6
Molecular Formula:C₂₃H₃₅NO₇
Molecular Weight:437.533
Hs Code.:

Synonyms:(2S)-piperidine-1,2-dicarboxylic acid 1-tert-butyl 2-<3'-(3,4,5-trimethoxyphenyl)propyl> diester

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Chemical Property of (2S)-piperidine-1,2-dicarboxylic acid 1-tert-butyl 2-<3'-(3,4,5-trimethoxyphenyl)propyl> diester

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Technology Process of (2S)-piperidine-1,2-dicarboxylic acid 1-tert-butyl 2-<3'-(3,4,5-trimethoxyphenyl)propyl> diester

There total 1 articles about (2S)-piperidine-1,2-dicarboxylic acid 1-tert-butyl 2-<3'-(3,4,5-trimethoxyphenyl)propyl> diester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 53560-26-2
3-(3,4,5-trimethoxyphenyl)propan-1-ol

: 26250-84-0
(S)-(-)-1-(tert-butoxycarbonyl)-2-piperidinecarboxylic acid

: 175721-87-6
(2S)-piperidine-1,2-dicarboxylic acid 1-tert-butyl 2-<3'-(3,4,5-trimethoxyphenyl)propyl> diester

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 23 ℃; for 3h;
DOI:10.1021/jm950798a

Reference yield:

: 175721-87-6
(2S)-piperidine-1,2-dicarboxylic acid 1-tert-butyl 2-<3'-(3,4,5-trimethoxyphenyl)propyl> diester

: 1027173-96-1
(S)-Piperidine-2-carboxylic acid 3-(3,4,5-trimethoxy-phenyl)-propyl ester

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 23 ℃; for 2h;
DOI:10.1021/jm950798a

Reference yield:

: 175721-87-6
(2S)-piperidine-1,2-dicarboxylic acid 1-tert-butyl 2-<3'-(3,4,5-trimethoxyphenyl)propyl> diester

: (S)-1-(2,2-Dimethyl-propylcarbamoyl)-piperidine-2-carboxylic acid 3-(3,4,5-trimethoxy-phenyl)-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: HCl / dioxane / 2 h / 23 °C

2: Et₃N / CH₂Cl₂ / 1 h / 23 °C

With hydrogenchloride; triethylamine; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jm950798a