9-hydroxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-methyl-2-oxo-1,2,3(S),4,4a(R),9(S),9a(S),10(R*)-octahydroanthracene

Base Information

Chemical Name:9-hydroxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-methyl-2-oxo-1,2,3(S*),4,4a(R*),9(S*),9a(S*),10(R*)-octahydroanthracene
CAS No.:74852-42-9
Molecular Formula:C₂₅H₂₈O₅S
Molecular Weight:440.56
Hs Code.:

Synonyms:9-hydroxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-methyl-2-oxo-1,2,3(S*),4,4a(R*),9(S*),9a(S*),10(R*)-octahydroanthracene

Suppliers and Price of 9-hydroxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-methyl-2-oxo-1,2,3(S*),4,4a(R*),9(S*),9a(S*),10(R*)-octahydroanthracene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 9-hydroxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-methyl-2-oxo-1,2,3(S*),4,4a(R*),9(S*),9a(S*),10(R*)-octahydroanthracene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 9-hydroxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-methyl-2-oxo-1,2,3(S*),4,4a(R*),9(S*),9a(S*),10(R*)-octahydroanthracene

There total 4 articles about 9-hydroxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-methyl-2-oxo-1,2,3(S*),4,4a(R*),9(S*),9a(S*),10(R*)-octahydroanthracene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 917-54-4
methyllithium

: 74852-41-8
2-acetoxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-oxo-1,4,4a(R*),9,9a(S*),10(R*)-hexahydroanthracene

: 74852-42-9
9-hydroxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-methyl-2-oxo-1,2,3(S*),4,4a(R*),9(S*),9a(S*),10(R*)-octahydroanthracene

Guidance literature:: In 1,2-dimethoxyethane; diethyl ether; at -20 ℃; for 1.5h;
DOI:10.1021/ja00530a041

Reference yield:

: 65174-13-2
2-acetoxy-3-(4'-methoxyphenylthio)-1,3-butadiene

: 74852-42-9
9-hydroxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-methyl-2-oxo-1,2,3(S*),4,4a(R*),9(S*),9a(S*),10(R*)-octahydroanthracene

Guidance literature:: Multi-step reaction with 4 steps

1: 61 percent / 2,6-di-tert-butyl-4-methylphenol, boron trifluoride etherate / CH₂Cl₂ / 1.) -78 deg C, 30 min, 2.) -25 deg C, 1.5 h

2: sodium borohydride / ethanol; ethyl acetate / 4 h / 0 °C

3: 486 mg / boron trifluoride etherate / acetone / 4 h / 0 °C

4: 39 percent / 1,2-dimethoxy-ethane; diethyl ether / 1.5 h / -20 °C

With sodium tetrahydroborate; 2,6-di-tert-butyl-4-methyl-phenol; boron trifluoride diethyl etherate; In 1,2-dimethoxyethane; diethyl ether; ethanol; dichloromethane; ethyl acetate; acetone;
DOI:10.1021/ja00530a041

Reference yield:

: 65174-00-7
2-acetoxy-5-hydroxy-3-(4'-methoxyphenylthio)-1,4,4a(R*),9a(S*)-tetrahydroanthraquinone

: 74852-42-9
9-hydroxy-5,10-isopropylidenedioxy-3-(4'-methoxyphenylthio)-9-methyl-2-oxo-1,2,3(S*),4,4a(R*),9(S*),9a(S*),10(R*)-octahydroanthracene

Guidance literature:: Multi-step reaction with 3 steps

1: sodium borohydride / ethanol; ethyl acetate / 4 h / 0 °C

2: 486 mg / boron trifluoride etherate / acetone / 4 h / 0 °C

3: 39 percent / 1,2-dimethoxy-ethane; diethyl ether / 1.5 h / -20 °C

With sodium tetrahydroborate; boron trifluoride diethyl etherate; In 1,2-dimethoxyethane; diethyl ether; ethanol; ethyl acetate; acetone;
DOI:10.1021/ja00530a041