3-[N¹-(carbobenzyloxy)-N²-(carbobenzyloxy)-N²-acetylhydrazino]-N,N-dimethylpropanamide

Base Information

• Chemical Name: 3-[N¹-(carbobenzyloxy)-N²-(carbobenzyloxy)-N²-acetylhydrazino]-N,N-dimethylpropanamide
• CAS No.: 255873-57-5
• Molecular Formula: C₂₃H₂₇N₃O₆
• Molecular Weight: 441.484

Synonyms:3-[N¹-(carbobenzyloxy)-N²-(carbobenzyloxy)-N²-acetylhydrazino]-N,N-dimethylpropanamide

Chemical Property of 3-[N¹-(carbobenzyloxy)-N²-(carbobenzyloxy)-N²-acetylhydrazino]-N,N-dimethylpropanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[N¹-(carbobenzyloxy)-N²-(carbobenzyloxy)-N²-acetylhydrazino]-N,N-dimethylpropanamide

There total 3 articles about 3-[N¹-(carbobenzyloxy)-N²-(carbobenzyloxy)-N²-acetylhydrazino]-N,N-dimethylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

acetic anhydride (108-24-7) + 3-[N1,N2-bis(carbobenzyloxy)hydrazino]-N,N-dimethylpropanamide (255873-55-3) → 3-[N1-(carbobenzyloxy)-N2-(carbobenzyloxy)-N2-acetylhydrazino]-N,N-dimethylpropanamide (255873-57-5)

Guidance literature:

With dmap; at 80 ℃; for 4h;

DOI:10.1021/jo9915123

Reference yield:

N,N-Dimethylacrylamide (2680-03-7,68761-83-1) → 3-[N1-(carbobenzyloxy)-N2-(carbobenzyloxy)-N2-acetylhydrazino]-N,N-dimethylpropanamide (255873-57-5)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine monohydrate / methanol / 2 h

2: 5.91 g / sodium hydroxide / diethyl ether; H₂O / 1 h

3: 86 percent / 4-(dimethylamino)pyridine / 4 h / 80 °C

With dmap; sodium hydroxide; hydrazine hydrate; In methanol; diethyl ether; water; 1: Addition / 2: Acylation / 3: Acetylation;

DOI:10.1021/jo9915123

Reference yield:

3-hydrazino-N,N-(dimethyl)propanamide (107746-30-5) → 3-[N1-(carbobenzyloxy)-N2-(carbobenzyloxy)-N2-acetylhydrazino]-N,N-dimethylpropanamide (255873-57-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 5.91 g / sodium hydroxide / diethyl ether; H₂O / 1 h

2: 86 percent / 4-(dimethylamino)pyridine / 4 h / 80 °C

With dmap; sodium hydroxide; In diethyl ether; water; 1: Acylation / 2: Acetylation;

DOI:10.1021/jo9915123

upstream raw materials:

acetic anhydride

3-[N¹,N²-bis(carbobenzyloxy)hydrazino]-N,N-dimethylpropanamide

N,N-Dimethylacrylamide

3-hydrazino-N,N-(dimethyl)propanamide

Downstream raw materials:

3-[N¹-phenoxycarbonylhydrazido][N²-acetylhydrazino]-N,N-dimethylpropanamide

3-[N¹-(phenethylamidohydrazido)-N²-acetylhydrazino]-N,N-dimethylpropanamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 255873-57-5 3-[N¹-(carbobenzyloxy)-N²-(carbobenzyloxy)-N²-acetylhydrazino]-N,N-dimethylpropanamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send