2,4-dichloro-3-(dimethylaminomethylene)-1,4-cyclohexadiene-1,5-dicarboxaldehyde

Base Information

• Chemical Name: 2,4-dichloro-3-(dimethylaminomethylene)-1,4-cyclohexadiene-1,5-dicarboxaldehyde
• CAS No.: 101392-95-4
• Molecular Formula: C₁₁H₁₁Cl₂NO₂
• Molecular Weight: 260.12
• Mol file: 101392-95-4.mol

Synonyms:2,4-dichloro-3-(dimethylaminomethylene)-1,4-cyclohexadiene-1,5-dicarboxaldehyde

Chemical Property of 2,4-dichloro-3-(dimethylaminomethylene)-1,4-cyclohexadiene-1,5-dicarboxaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4-dichloro-3-(dimethylaminomethylene)-1,4-cyclohexadiene-1,5-dicarboxaldehyde

There total 3 articles about 2,4-dichloro-3-(dimethylaminomethylene)-1,4-cyclohexadiene-1,5-dicarboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

1,3-Cyclohexanedione (30182-67-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 2,4-dichloro-3-(dimethylaminomethylene)-1,4-cyclohexadiene-1,5-dicarboxaldehyde (101392-95-4)

Guidance literature:

With trichlorophosphate; at 5 deg C, then at 20 deg C for 24 h;

DOI:10.1016/S0040-4039(00)94931-1

Reference yield:

3-chloro-2-cyclohexenone (5682-75-7) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 2,4-dichloro-3-(dimethylaminomethylene)-1,4-cyclohexadiene-1,5-dicarboxaldehyde (101392-95-4)

Guidance literature:

With trichlorophosphate; Yield given. Multistep reaction; 1.) 5 deg C, 2.) 20 deg C, 36 h;

DOI:10.1021/jo00389a016

Reference yield:

3-bromo-2-cyclohexen-1-one (56671-81-9) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 2,4-dichloro-3-(dimethylaminomethylene)-1,4-cyclohexadiene-1,5-dicarboxaldehyde (101392-95-4)

Guidance literature:

With trichlorophosphate; Yield given. Multistep reaction; 1.) 5 deg C, 2.) 20 deg C, 36 h;

DOI:10.1021/jo00389a016

upstream raw materials:

1,3-Cyclohexanedione

N,N-dimethyl-formamide

3-chloro-2-cyclohexenone

3-bromo-2-cyclohexen-1-one

Downstream raw materials:

2,4-dichlorobenzene-1,3,5-tricarbaldehyde