(E)-ethyl 3-(4-(4-(N-(4-((diethoxyphosphoryl)methyl)benzyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylate

Base Information

Chemical Name:(E)-ethyl 3-(4-(4-(N-(4-((diethoxyphosphoryl)methyl)benzyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylate
CAS No.:1234367-46-4
Molecular Formula:C₃₀H₃₄F₂NO₈PS
Molecular Weight:637.638
Hs Code.:

Synonyms:(E)-ethyl 3-(4-(4-(N-(4-((diethoxyphosphoryl)methyl)benzyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylate

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Chemical Property of (E)-ethyl 3-(4-(4-(N-(4-((diethoxyphosphoryl)methyl)benzyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylate

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Technology Process of (E)-ethyl 3-(4-(4-(N-(4-((diethoxyphosphoryl)methyl)benzyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylate

There total 1 articles about (E)-ethyl 3-(4-(4-(N-(4-((diethoxyphosphoryl)methyl)benzyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 187541-61-3
ethyl E-3-[3,4,5-trifluorophenyl]-2-methyl-propenoate

: 1234367-45-3
diethyl 4-((4-hydroxyphenylsulfonamido)methyl)benzylphosphonate

: 1234367-46-4
(E)-ethyl 3-(4-(4-(N-(4-((diethoxyphosphoryl)methyl)benzyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylate

Guidance literature:: diethyl 4-((4-hydroxyphenylsulfonamido)methyl)benzylphosphonate; With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 1.5h;

ethyl E-3-[3,4,5-trifluorophenyl]-2-methyl-propenoate; In N,N-dimethyl-formamide; at 90 ℃;

Reference yield: 35.0%

: 1234367-46-4
(E)-ethyl 3-(4-(4-(N-(4-((diethoxyphosphoryl)methyl)benzyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylate

: 1234367-47-5
(E)-3-(4-(4-(N-(4-((diethoxyphosphoryl)methyl)benzyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylic acid

Guidance literature:: (E)-ethyl 3-(4-(4-(N-(4-((diethoxyphosphoryl)methyl)benzyl)sulfamoyl)phenoxy)-3,5-difluorophenyl)-2-methylacrylate; With water; lithium hydroxide; In tetrahydrofuran; at 25 ℃; for 1h;

With hydrogenchloride; In water; pH=4 - 5;