C₂₇H₃₁NO₃Si

Base Information

• Chemical Name: C₂₇H₃₁NO₃Si
• CAS No.: 1435943-90-0
• Molecular Formula: C₂₇H₃₁NO₃Si
• Molecular Weight: 445.634
• Mol file: 1435943-90-0.mol

Synonyms:C₂₇H₃₁NO₃Si

Chemical Property of C₂₇H₃₁NO₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₃₁NO₃Si

There total 2 articles about C₂₇H₃₁NO₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

α-hydroxyphenylacetic acid allyl ester (6282-41-3) + O-(tert-butyl)diphenylsilylhydroxylamine (103587-51-5) → C27H31NO3Si (1435943-90-0)

Guidance literature:

α-hydroxyphenylacetic acid allyl ester; With trifluoromethylsulfonic anhydride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at -78 ℃; for 0.25h; Inert atmosphere;

O-(tert-butyl)diphenylsilylhydroxylamine; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1002/asia.201200820

Reference yield:

MANDELIC ACID (611-71-2,611-72-3,17199-29-0,90-64-2) → C27H31NO3Si (1435943-90-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 20 °C / Inert atmosphere

2.1: N-ethyl-N,N-diisopropylamine; trifluoromethylsulfonic anhydride / dichloromethane / 0.25 h / -78 °C / Inert atmosphere

2.2: 2 h / 20 °C / Inert atmosphere

With trifluoromethylsulfonic anhydride; potassium carbonate; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/asia.201200820

Reference yield: 60.0%

C27H31NO3Si (1435943-90-0) → C24H27NO3Si (1435943-74-0)

Guidance literature:

With morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

DOI:10.1002/asia.201200820

upstream raw materials:

MANDELIC ACID

α-hydroxyphenylacetic acid allyl ester

O-(tert-butyl)diphenylsilylhydroxylamine

Downstream raw materials:

C₂₄H₂₇NO₃Si

C₃₄H₄₁NO₆Si

C₁₈H₂₁NO₅