N-<4-<<(5-Amino-6-carbamoylpyrazinyl)methyl>methylamino>benzoyl>-L-glutamic Acid

Base Information

Chemical Name:N-<4-<<(5-Amino-6-carbamoylpyrazinyl)methyl>methylamino>benzoyl>-L-glutamic Acid
CAS No.:96797-09-0
Molecular Formula:C₁₉H₂₂N₆O₆
Molecular Weight:430.42
Hs Code.:

Synonyms:N-<4-<<(5-Amino-6-carbamoylpyrazinyl)methyl>methylamino>benzoyl>-L-glutamic Acid

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Chemical Property of N-<4-<<(5-Amino-6-carbamoylpyrazinyl)methyl>methylamino>benzoyl>-L-glutamic Acid

Chemical Property:

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Technology Process of N-<4-<<(5-Amino-6-carbamoylpyrazinyl)methyl>methylamino>benzoyl>-L-glutamic Acid

There total 4 articles about N-<4-<<(5-Amino-6-carbamoylpyrazinyl)methyl>methylamino>benzoyl>-L-glutamic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 96797-08-9
Diethyl N-<4-<<(5-Amino-6-carbamoylpyrazinyl)methyl>methylamino>benzoyl>-L-glutamate

: 96797-09-0
N-<4-<<(5-Amino-6-carbamoylpyrazinyl)methyl>methylamino>benzoyl>-L-glutamic Acid

Guidance literature:: With sodium hydroxide; In ethanol; for 120h; Ambient temperature;

Reference yield:

: 2378-95-2
diethyl N-<4-(methylamino)benzoyl>-L-glutamate

: 96797-09-0
N-<4-<<(5-Amino-6-carbamoylpyrazinyl)methyl>methylamino>benzoyl>-L-glutamic Acid

Guidance literature:: Multi-step reaction with 3 steps

1: 40 percent / potassium carbonate / dimethylsulfoxide / 144 h / Ambient temperature

2: 30 percent / phosphorus trichloride / tetrahydrofuran / 2 h, 0 deg C; then 5 h r.t.

3: 66 percent / 0.1 N aq. sodium hydroxide / ethanol / 120 h / Ambient temperature

With sodium hydroxide; potassium carbonate; phosphorus trichloride; In tetrahydrofuran; ethanol; dimethyl sulfoxide;

Reference yield:

: 96797-06-7
3-Amino-6-bromomethyl-2-carbamoylpyrazine 4-Oxide

: 96797-09-0
N-<4-<<(5-Amino-6-carbamoylpyrazinyl)methyl>methylamino>benzoyl>-L-glutamic Acid

Guidance literature:: Multi-step reaction with 3 steps

1: 40 percent / potassium carbonate / dimethylsulfoxide / 144 h / Ambient temperature

2: 30 percent / phosphorus trichloride / tetrahydrofuran / 2 h, 0 deg C; then 5 h r.t.

3: 66 percent / 0.1 N aq. sodium hydroxide / ethanol / 120 h / Ambient temperature

With sodium hydroxide; potassium carbonate; phosphorus trichloride; In tetrahydrofuran; ethanol; dimethyl sulfoxide;