1-{3'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N⁴-isobutyrylcytosine

Base Information

• Chemical Name: 1-{3'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N⁴-isobutyrylcytosine
• CAS No.: 619277-23-5
• Molecular Formula: C₄₁H₄₁N₃O₉
• Molecular Weight: 719.791

Synonyms:1-{3'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N⁴-isobutyrylcytosine

Chemical Property of 1-{3'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N⁴-isobutyrylcytosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-{3'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N⁴-isobutyrylcytosine

There total 9 articles about 1-{3'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N⁴-isobutyrylcytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

1-{4'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N4-isobutyrylcytosine (619277-07-5) → 1-{3'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N4-isobutyrylcytosine (619277-23-5)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1002/hlca.200390118

Reference yield:

4,4'-dimethoxytrityl chloride (40615-36-9) → 1-{3'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N4-isobutyrylcytosine (619277-23-5)

Guidance literature:

Multi-step reaction with 4 steps

1: collodine / CH₂Cl₂ / 12 h / 20 °C

2: 15 g / NaHCO₃; citric acid

3: 78 percent / pyridine; CH₂Cl₂ / 3 h / -10 °C

4: 48 percent / Et₃N / CH₂Cl₂ / 12 h / 20 °C

With collodine; sodium hydrogencarbonate; triethylamine; citric acid; In pyridine; dichloromethane;

DOI:10.1002/hlca.200390118

Reference yield:

1-α-L-arabinopyranosylcytosine (55530-11-5) → 1-{3'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N4-isobutyrylcytosine (619277-23-5)

Guidance literature:

Multi-step reaction with 6 steps

1: 6.4 g / dimethylformamide / 15 h / 20 °C

2: collidine; molecular sieves (4 Angstroem) / dimethylformamide / 3 h / 20 °C

3: collodine / CH₂Cl₂ / 12 h / 20 °C

4: 15 g / NaHCO₃; citric acid

5: 78 percent / pyridine; CH₂Cl₂ / 3 h / -10 °C

6: 48 percent / Et₃N / CH₂Cl₂ / 12 h / 20 °C

With 2,3,5-trimethyl-pyridine; 4 A molecular sieve; collodine; sodium hydrogencarbonate; triethylamine; citric acid; In pyridine; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/hlca.200390118

upstream raw materials:

1-{4'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N⁴-isobutyrylcytosine

4,4'-dimethoxytrityl chloride

1-α-L-arabinopyranosylcytosine

1-(α-L-arabinopyranosyl)-N⁴-isobutyrylcytosine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 619277-23-5 1-{3'-O-benzoyl-2'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-arabinopyranosyl}-N⁴-isobutyrylcytosine

Send

Send

Metric Ton KG G Pound L ML

Send

Send