2-[3-(3-benzyloxy-phenoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Base Information

• Chemical Name: 2-[3-(3-benzyloxy-phenoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
• CAS No.: 765908-39-2
• Molecular Formula: C₂₅H₂₇BO₄
• Molecular Weight: 402.298
• Mol file: 765908-39-2.mol

Synonyms:2-[3-(3-benzyloxy-phenoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Chemical Property of 2-[3-(3-benzyloxy-phenoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[3-(3-benzyloxy-phenoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

There total 2 articles about 2-[3-(3-benzyloxy-phenoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3-(benzyloxy)phenylboronic acid (156682-54-1) + 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (214360-76-6) → 2-[3-(3-benzyloxy-phenoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (765908-39-2)

Guidance literature:

With copper diacetate; triethylamine;

DOI:10.1016/j.tetlet.2004.07.014

Reference yield:

2-(3-(benzyloxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (765908-38-1) → 2-[3-(3-benzyloxy-phenoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (765908-39-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / polystyrene boronic acid; aq. HCl / acetonitrile

2: 89 percent / Cu(OAc)2; NEt₃

With hydrogenchloride; copper diacetate; polystyrene boronic acid; triethylamine; In acetonitrile;

DOI:10.1016/j.tetlet.2004.07.014

Reference yield: 96.0%

2-[3-(3-benzyloxy-phenoxy)-phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (765908-39-2) → 3-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-phenol (765908-41-6)

Guidance literature:

With hydrogen; palladium on activated charcoal;

DOI:10.1016/j.tetlet.2004.07.014

upstream raw materials:

3-(benzyloxy)phenylboronic acid

3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

2-(3-(benzyloxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Downstream raw materials:

3-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-phenol

C₁₉H₁₇BO₄