(1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide

Base Information

Chemical Name:(1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide
CAS No.:1036488-28-4
Molecular Formula:C₂₃H₃₁BrN₆O₂
Molecular Weight:503.442
Hs Code.:

Synonyms:(1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide

Suppliers and Price of (1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide

There total 1 articles about (1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 179756-43-5,1036488-30-8
(S)-tert-butyl 3-(4-aminophenoxy)pyrrolidine-1-carboxylate

: 958227-60-6
(1S,2R)-2-(2-chloro-5-bromo-pyrimidin-4-ylamino)-cyclopentanecarboxylic acid isopropylamide

: 1036488-28-4
(1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide

Guidance literature:: With hydrogenchloride; methanol; In 1,4-dioxane; at 130 ℃; for 0.666667h; Microwave irradiation;

Reference yield:

: 29943-42-8,143562-54-3
Tetrahydro-4H-pyran-4-one

: 1036488-28-4
(1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide

: 1036649-34-9
(1S,2R)-2-(5-bromo-2-(4-((S)-1-(tetrahydropyran-4-yl)-pyrrolidin-3-yloxy)-phenylamino)-pyrimidin-4-ylamino)-cyclopentanecarboxylic acid isopropylamide

Guidance literature:: Tetrahydro-4H-pyran-4-one; (1S,2R)-2-{5-bromo-2-[4-((S)-pyrrolidin-3-yloxy)-phenylamino]-pyrimidin-4-ylamino}-cyclopentanecarboxylic acid isopropylamide; With acetic acid; In N,N-dimethyl acetamide; at 20 ℃; for 0.5h;

With sodium tris(acetoxy)borohydride; In N,N-dimethyl acetamide; at 20 ℃; for 2h;