3-(4-Fluoro-benzenesulfonyl)-azetidine-1-carboxylic acid tert-butyl ester

Base Information

Chemical Name:3-(4-Fluoro-benzenesulfonyl)-azetidine-1-carboxylic acid tert-butyl ester
CAS No.:887593-66-0
Molecular Formula:C₁₄H₁₈FNO₄S
Molecular Weight:315.366
Hs Code.:
DSSTox Substance ID:DTXSID20698822
Wikidata:Q82629316
Mol file:887593-66-0.mol

Synonyms:887593-66-0;3-(4-FLUORO-BENZENESULFONYL)-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;DTXSID20698822;tert-Butyl 3-((4-fluorophenyl)sulfonyl)azetidine-1-carboxylate;tert-Butyl 3-(4-fluorobenzene-1-sulfonyl)azetidine-1-carboxylate;TERT-BUTYL 3-(4-FLUOROBENZENESULFONYL)AZETIDINE-1-CARBOXYLATE

Suppliers and Price of 3-(4-Fluoro-benzenesulfonyl)-azetidine-1-carboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3-(4-fluoro-benzenesulfonyl)-azetidine-1-carboxylicacidtert-butylester 95
10g
$ 4113.00

Labseeker
3-(4-fluoro-benzenesulfonyl)-azetidine-1-carboxylicacidtert-butylester 95
5g
$ 3025.00

Labseeker
3-(4-fluoro-benzenesulfonyl)-azetidine-1-carboxylicacidtert-butylester 95
2g
$ 1833.00

American Custom Chemicals Corporation
3-(4-FLUORO-BENZENESULFONYL)-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00%
5MG
$ 497.95

Total 1 raw suppliers

Chemical Property of 3-(4-Fluoro-benzenesulfonyl)-azetidine-1-carboxylic acid tert-butyl ester

Chemical Property:

PSA：72.06000
LogP:3.23740
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:315.09405739
Heavy Atom Count:21
Complexity:480

Purity/Quality:: 3-(4-fluoro-benzenesulfonyl)-azetidine-1-carboxylicacidtert-butylester 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CC(C1)S(=O)(=O)C2=CC=C(C=C2)F

Technology Process of 3-(4-Fluoro-benzenesulfonyl)-azetidine-1-carboxylic acid tert-butyl ester

There total 3 articles about 3-(4-Fluoro-benzenesulfonyl)-azetidine-1-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl 3-[(4-fluorophenyl)thio]azetidine-1-carboxylate

: 887593-66-0
C₁₄H₁₈FNO₄S

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃;
DOI:10.1002/anie.201711828

Reference yield:

: 371-42-6
4-Fluorothiophenol

: 887593-66-0
C₁₄H₁₈FNO₄S

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium t-butanolate / dimethyl sulfoxide / 0.5 h / 20 °C

1.2: 80 °C

2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C

With 3-chloro-benzenecarboperoxoic acid; sodium t-butanolate; In dichloromethane; dimethyl sulfoxide;
DOI:10.1002/anie.201711828

Reference yield:

: 1064194-10-0
3-bromo-azetidine-1-carboxylic acid tert-butyl ester

: 887593-66-0
C₁₄H₁₈FNO₄S

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium t-butanolate / dimethyl sulfoxide / 0.5 h / 20 °C

1.2: 80 °C

2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C

With 3-chloro-benzenecarboperoxoic acid; sodium t-butanolate; In dichloromethane; dimethyl sulfoxide;
DOI:10.1002/anie.201711828