tert-butyl 3-(2-(3-amino-5-(trifluoromethyl)phenoxy)-5-nitrophenyl)prop-2-ynylcarbamate

Base Information

Chemical Name:tert-butyl 3-(2-(3-amino-5-(trifluoromethyl)phenoxy)-5-nitrophenyl)prop-2-ynylcarbamate
CAS No.:1613588-75-2
Molecular Formula:C₂₁H₂₀F₃N₃O₅
Molecular Weight:451.402
Hs Code.:

Synonyms:tert-butyl 3-(2-(3-amino-5-(trifluoromethyl)phenoxy)-5-nitrophenyl)prop-2-ynylcarbamate

Suppliers and Price of tert-butyl 3-(2-(3-amino-5-(trifluoromethyl)phenoxy)-5-nitrophenyl)prop-2-ynylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl 3-(2-(3-amino-5-(trifluoromethyl)phenoxy)-5-nitrophenyl)prop-2-ynylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl 3-(2-(3-amino-5-(trifluoromethyl)phenoxy)-5-nitrophenyl)prop-2-ynylcarbamate

There total 4 articles about tert-butyl 3-(2-(3-amino-5-(trifluoromethyl)phenoxy)-5-nitrophenyl)prop-2-ynylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1613588-74-1
tert-butyl 3-(2-fluoro-5-nitrophenyl)prop-2-ynylcarbamate

: 401-86-5
3-amino-5-(1,1,1-trilfluoromethyl)phenol

: 1613588-75-2
tert-butyl 3-(2-(3-amino-5-(trifluoromethyl)phenoxy)-5-nitrophenyl)prop-2-ynylcarbamate

Guidance literature:: 3-amino-5-(1,1,1-trilfluoromethyl)phenol; With potassium carbonate; In N,N-dimethyl-formamide; at 70 ℃; for 0.5h;

tert-butyl 3-(2-fluoro-5-nitrophenyl)prop-2-ynylcarbamate; In N,N-dimethyl-formamide; at 70 ℃; for 16h;

Reference yield:

: 701-45-1
2-bromo-1-fluoro-4-nitrobenzene

: 1613588-75-2
tert-butyl 3-(2-(3-amino-5-(trifluoromethyl)phenoxy)-5-nitrophenyl)prop-2-ynylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / acetonitrile / 48 h / 20 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 70 °C

2.2: 16 h / 70 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium carbonate; triethylamine; In N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 92136-39-5
N-tert-Butoxycarbonyl-1-amino-3-propyne

: 1613588-75-2
tert-butyl 3-(2-(3-amino-5-(trifluoromethyl)phenoxy)-5-nitrophenyl)prop-2-ynylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / acetonitrile / 48 h / 20 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 70 °C

2.2: 16 h / 70 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium carbonate; triethylamine; In N,N-dimethyl-formamide; acetonitrile;