(2'R,3'S)-2',7,10-tris-O-(triethylsilyl)-2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-N-desbenzoyl-N-(t-butoxycarbonyl)taxol

Base Information

Chemical Name:(2'R,3'S)-2',7,10-tris-O-(triethylsilyl)-2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-N-desbenzoyl-N-(t-butoxycarbonyl)taxol
CAS No.:159212-06-3
Molecular Formula:C₆₁H₉₄ClNO₁₄Si₃
Molecular Weight:1185.13
Hs Code.:

Synonyms:(2'R,3'S)-2',7,10-tris-O-(triethylsilyl)-2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-N-desbenzoyl-N-(t-butoxycarbonyl)taxol

Suppliers and Price of (2'R,3'S)-2',7,10-tris-O-(triethylsilyl)-2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-N-desbenzoyl-N-(t-butoxycarbonyl)taxol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2'R,3'S)-2',7,10-tris-O-(triethylsilyl)-2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-N-desbenzoyl-N-(t-butoxycarbonyl)taxol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2'R,3'S)-2',7,10-tris-O-(triethylsilyl)-2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-N-desbenzoyl-N-(t-butoxycarbonyl)taxol

There total 3 articles about (2'R,3'S)-2',7,10-tris-O-(triethylsilyl)-2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-N-desbenzoyl-N-(t-butoxycarbonyl)taxol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-7,10-bis-O-(triethylsilyl)baccatin III

: cis-1-(t-butoxycarbonyl)-3-triethylsilyloxy-4-phenylazetidin-2-one

: 159212-06-3
(2'R,3'S)-2',7,10-tris-O-(triethylsilyl)-2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-N-desbenzoyl-N-(t-butoxycarbonyl)taxol

Guidance literature:: 2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-7,10-bis-O-(triethylsilyl)baccatin III; With lithium hexamethyldisilazane; In tetrahydrofuran; hexane; at -45 ℃; for 0.5h;

cis-1-(t-butoxycarbonyl)-3-triethylsilyloxy-4-phenylazetidin-2-one; In tetrahydrofuran; hexane; at -45 - 0 ℃; for 1h;

With acetic acid; In tetrahydrofuran; hexane;

Reference yield:

: 2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-7,10-bis-O-(triethylsilyl)baccatin III

: 149198-47-0
tert-butyl (3R,4S)-2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate

: 159212-06-3
(2'R,3'S)-2',7,10-tris-O-(triethylsilyl)-2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-N-desbenzoyl-N-(t-butoxycarbonyl)taxol

Guidance literature:: With LiN(SiMe₃)2; acetic acid; In tetrahydrofuran; hexane;

Reference yield:

: cis-1-(tert-butoxycarbonyl)-3-triethylsilyloxy-4-phenylazetidin-2-one

: 2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-7,10-bis-O-(triethylsilyl)baccatin III

: 159212-06-3
(2'R,3'S)-2',7,10-tris-O-(triethylsilyl)-2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-N-desbenzoyl-N-(t-butoxycarbonyl)taxol

Guidance literature:: 2-desbenzoyl-2-(4-chlorobenzoyl)-10-deacetyl-7,10-bis-O-(triethylsilyl)baccatin III; With lithium hexamethyldisilazane; In tetrahydrofuran; hexane; at -45 ℃; for 0.5h;

cis-1-(tert-butoxycarbonyl)-3-triethylsilyloxy-4-phenylazetidin-2-one; With acetic acid; In tetrahydrofuran; at 0 ℃; for 1h;