N-[1-benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohexyl]-N,N-dimethylamine

Base Information

Chemical Name:N-[1-benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohexyl]-N,N-dimethylamine
CAS No.:1004542-33-9
Molecular Formula:C₂₅H₂₉F₃N₂
Molecular Weight:414.514
Hs Code.:

Synonyms:N-[1-benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohexyl]-N,N-dimethylamine

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Chemical Property of N-[1-benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohexyl]-N,N-dimethylamine

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Technology Process of N-[1-benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohexyl]-N,N-dimethylamine

There total 3 articles about N-[1-benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohexyl]-N,N-dimethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1004548-17-7
(+/-)-[1-Benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohex-3-enyl]-dimethylamine

: 1004542-33-9
N-[1-benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohexyl]-N,N-dimethylamine

: 1004542-31-7
N-[1-benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohexyl]-N,N-dimethylamine

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In methanol; at 40 ℃; for 4h; under 2250.23 Torr;

Reference yield:

: 475098-34-1
4-benzyl-4-(dimethylamino)cyclohexanone

: 1004542-33-9
N-[1-benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohexyl]-N,N-dimethylamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluorormethanesulfonic acid / dichloromethane / 72 h / 20 °C

1.2: 0.17 h

2.1: hydrogen / 5%-palladium/activated carbon / methanol / 4 h / 40 °C / 2250.23 Torr

With trifluorormethanesulfonic acid; hydrogen; 5%-palladium/activated carbon; In methanol; dichloromethane;

Reference yield:

: 3613-06-7
3-methyl-1H-indole-5-carbonitrile

: 1004542-33-9
N-[1-benzyl-4-(3-methyl-5-trifluoromethyl-1H-indol-2-yl)cyclohexyl]-N,N-dimethylamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluorormethanesulfonic acid / dichloromethane / 72 h / 20 °C

1.2: 0.17 h

2.1: hydrogen / 5%-palladium/activated carbon / methanol / 4 h / 40 °C / 2250.23 Torr

With trifluorormethanesulfonic acid; hydrogen; 5%-palladium/activated carbon; In methanol; dichloromethane;