7-Bromo-4-chloro-2-phenylquinazoline

Base Information

• Chemical Name: 7-Bromo-4-chloro-2-phenylquinazoline
• CAS No.: 887592-38-3
• Molecular Formula: C14H8 Br Cl N2
• Molecular Weight: 319.58
• DSSTox Substance ID: DTXSID90695409
• Wikidata: Q82624577
• Mol file: 887592-38-3.mol

Synonyms:7-Bromo-4-chloro-2-phenylquinazoline;887592-38-3;7-BROMO-4-CHLORO-2-PHENYL-QUINAZOLINE;SCHEMBL13312483;DTXSID90695409;AMY27568

Chemical Property of 7-Bromo-4-chloro-2-phenylquinazoline

Chemical Property:

• PSA: 25.78000
• LogP: 4.71270
• XLogP3: 5.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 317.95594
• Heavy Atom Count: 18
• Complexity: 283

Purity/Quality:

7-bromo-4-chloro-2-phenyl-quinazoline 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC3=C(C=CC(=C3)Br)C(=N2)Cl

Technology Process of 7-Bromo-4-chloro-2-phenylquinazoline

There total 1 articles about 7-Bromo-4-chloro-2-phenylquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H9BrN2O (1152237-10-9) → C14H8BrClN2 (887592-38-3)

Guidance literature:

With trichlorophosphate; Reflux; Neat (no solvent);

Reference yield: 35.0%

4-(2-AMINOETHYL)MORPHOLINE (2038-03-1) + C14H8BrClN2 (887592-38-3) → C20H21BrN4O (1152237-49-4)

Guidance literature:

In ethanol; at 80 ℃; for 3h; Sealed tube;

upstream raw materials:

C₁₄H₉BrN₂O

Downstream raw materials:

C₂₀H₂₁BrN₄O

Refernces