(2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Base Information

Chemical Name:(2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester
CAS No.:867156-31-8
Molecular Formula:C₄₂H₆₅NO₇
Molecular Weight:695.981
Hs Code.:

Synonyms:(2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Suppliers and Price of (2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

There total 1 articles about (2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 69863-36-1
N-benzyloxycarbonyl-O-benzyl-L-threonine

: 467224-46-0
(2S,3R)-2-((4S,5S)-2,2,5-Trimethyl-[1,3]dioxan-4-yl)-hexadecan-3-ol

: 867156-31-8
(2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Guidance literature:: With dmap; camphor-10-sulfonic acid; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 25 ℃; for 0.75h;
DOI:10.1021/jo050628y

Reference yield:

: 867156-31-8
(2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

: 867156-32-9
(2S,3R)-2-Amino-3-benzyloxy-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; ethylenediamine; In methanol; at 25 ℃; for 0.5h;
DOI:10.1021/jo050628y

Reference yield:

: 867156-31-8
(2S,3R)-3-Benzyloxy-2-benzyloxycarbonylamino-butyric acid (R)-1-[(S)-1-((4S,5S)-2,2,5-trimethyl-[1,3]dioxan-4-yl)-ethyl]-tetradecyl ester

: 867156-45-4
(3S,6S,9S,12R,13R,14R,15R)-3-((R)-1-Benzyloxy-ethyl)-13-hydroxy-6-((R)-1-hydroxy-ethyl)-9-isopropyl-12,14-dimethyl-15-tridecyl-1-oxa-4,7,10-triaza-cyclopentadecane-2,5,8,11-tetraone

Guidance literature:: Multi-step reaction with 7 steps

1: H₂ / Pd/C-ethylenediamine complex / methanol / 0.5 h / 25 °C

2: 79 mg / HOBt; EDCI / dimethylformamide / 0.5 h / 25 °C

3: 99 percent / AcOH / H₂O; tetrahydrofuran / 14 h / 25 °C

4: 88 percent / TEMPO; KBr; NaClO / NaHCO₃ / CH₂Cl₂; H₂O / 0.5 h / 0 °C

5: 99 percent / 2-methyl-2-butene; NaClO₂; NaH₂PO₄ / 2-methyl-propan-2-ol; H₂O / 0.25 h / 25 °C

6: 99 percent / CH₂Cl₂ / 1 h / 0 °C

7: 15 mg / diethyl cyanophosphonate; triethylamine / dimethylformamide / 20 h / 0 - 25 °C

With 2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; diethyl cyanophosphonate; hydrogen; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium bromide; palladium on activated charcoal; sodium hydrogencarbonate; ethylenediamine; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1021/jo050628y