S₁₂-L-Phe-L-His-OMe

Base Information

• Chemical Name: S₁₂-L-Phe-L-His-OMe
• CAS No.: 133230-73-6
• Molecular Formula: C₂₉H₄₄N₄O₅
• Molecular Weight: 528.692
• Mol file: 133230-73-6.mol

Synonyms:S₁₂-L-Phe-L-His-OMe

Chemical Property of S₁₂-L-Phe-L-His-OMe

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S₁₂-L-Phe-L-His-OMe

There total 3 articles about S₁₂-L-Phe-L-His-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-Dodecyloxycarbonylamino-3-phenyl-propionic acid (133230-66-7) + L-histidine methyl ester dihydrochloride (7389-87-9) → S12-L-Phe-L-His-OMe (133230-73-6)

Guidance literature:

With dicyclohexyl-carbodiimide;

DOI:10.1021/jo00012a019

Reference yield:

n-dodecyl chloroformate (24460-74-0) → S12-L-Phe-L-His-OMe (133230-73-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent

2: 70 percent / dicyclohexylcarbodiimide

With dicyclohexyl-carbodiimide;

DOI:10.1021/jo00012a019

Reference yield:

L-phenylalanine (63-91-2,25191-15-5,658-69-5,67675-33-6) → S12-L-Phe-L-His-OMe (133230-73-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent

2: 70 percent / dicyclohexylcarbodiimide

With dicyclohexyl-carbodiimide;

DOI:10.1021/jo00012a019

upstream raw materials:

2-Dodecyloxycarbonylamino-3-phenyl-propionic acid

L-histidine methyl ester dihydrochloride

n-dodecyl chloroformate

L-phenylalanine

Downstream raw materials:

S₁₂-L-Phe-L-His-OH

Refernces