4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid

Base Information

Chemical Name:4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid
CAS No.:1610889-99-0
Molecular Formula:C₁₄H₁₂F₃NO₂S₂
Molecular Weight:347.382
Hs Code.:

Synonyms:4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid

Suppliers and Price of 4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid

There total 11 articles about 4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1610889-98-9
4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid ethyl ester

: 1610889-99-0
4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid

Guidance literature:: With water; potassium carbonate; In ethanol; at 20 ℃; for 16h;

Reference yield:

: 1242643-04-4
3,3-difluoro-3-(4-fluorophenyl)propan-1-ol

: 1610889-99-0
4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: carbon tetrabromide; triphenylphosphine / dichloromethane / 1 h / 0 - 20 °C

2: potassium carbonate / acetone / 16 h / 80 °C

3: water; potassium carbonate / ethanol / 16 h / 20 °C

With carbon tetrabromide; water; potassium carbonate; triphenylphosphine; In ethanol; dichloromethane; acetone;

Reference yield:

: 1242643-03-3
acetic acid [3,3-difluoro-3-(4-fluorophenyl)propyl] ester

: 1610889-99-0
4-[[3,3-difluoro-3-(4-fluorophenyl)propyl]sulfanyl]-2-methylthiazole-5-carboxylic acid

Guidance literature:: Multi-step reaction with 4 steps

1: water; sodium hydroxide / ethanol / 1 h / 0 - 20 °C

2: carbon tetrabromide; triphenylphosphine / dichloromethane / 1 h / 0 - 20 °C

3: potassium carbonate / acetone / 16 h / 80 °C

4: water; potassium carbonate / ethanol / 16 h / 20 °C

With carbon tetrabromide; water; potassium carbonate; triphenylphosphine; sodium hydroxide; In ethanol; dichloromethane; acetone;