C₄₂H₄₃N₃O₂

Base Information

• Chemical Name: C₄₂H₄₃N₃O₂
• CAS No.: 1616852-94-8
• Molecular Formula: C₄₂H₄₃N₃O₂
• Molecular Weight: 621.822
• Mol file: 1616852-94-8.mol

Synonyms:C₄₂H₄₃N₃O₂

Chemical Property of C₄₂H₄₃N₃O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₄₂H₄₃N₃O₂

There total 11 articles about C₄₂H₄₃N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

1-chloro-1,2-dihydroacenaphthylene (40745-49-1) + C30H35N3O2 (1616856-86-0) → C42H43N3O2 (1616852-94-8)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

Reference yield:

methyl (2-nitrophenyl)acetate (30095-98-8) → C42H43N3O2 (1616852-94-8)

Guidance literature:

Multi-step reaction with 5 steps

1.1: hydrogen; palladium 10% on activated carbon / methanol / 20 °C / 760.05 Torr

2.1: acetic acid / dichloromethane / 2 h / 20 °C

2.2: 40 °C

3.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C

3.2: 0.33 h

3.3: -78 - 20 °C

4.1: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

5.1: triethylamine / N,N-dimethyl-formamide / 12 h / 20 °C

With palladium 10% on activated carbon; hydrogen; acetic acid; triethylamine; trifluoroacetic acid; lithium diisopropyl amide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

1(2H)-acenaphthylenone (2235-15-6) → C42H43N3O2 (1616852-94-8)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tetrahydroborate / methanol / 2 h / 20 °C

2: N,N-dimethyl-formamide; thionyl chloride / dichloromethane / 2 h / -20 °C

3: triethylamine / N,N-dimethyl-formamide / 12 h / 20 °C

With sodium tetrahydroborate; thionyl chloride; triethylamine; N,N-dimethyl-formamide; In methanol; dichloromethane; N,N-dimethyl-formamide;

upstream raw materials:

naphth-1-yl acetic acid

naphthalen-1-yl-acetyl chloride

N,N-bis(phenylmethyl)-2-oxiranemethanamine

C₃₅H₄₃N₃O₄