4-((2-oxo-1-phenylpropyl)amino)-3-benzoyl-7-dimethylaminocoumarin

Base Information

• Chemical Name: 4-((2-oxo-1-phenylpropyl)amino)-3-benzoyl-7-dimethylaminocoumarin
• CAS No.: 1439370-56-5
• Molecular Formula: C₂₇H₂₄N₂O₄
• Molecular Weight: 440.499
• Mol file: 1439370-56-5.mol

Synonyms:4-((2-oxo-1-phenylpropyl)amino)-3-benzoyl-7-dimethylaminocoumarin

Chemical Property of 4-((2-oxo-1-phenylpropyl)amino)-3-benzoyl-7-dimethylaminocoumarin

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-((2-oxo-1-phenylpropyl)amino)-3-benzoyl-7-dimethylaminocoumarin

There total 1 articles about 4-((2-oxo-1-phenylpropyl)amino)-3-benzoyl-7-dimethylaminocoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

3-benzoyl-7-N,N-dimethylamino-4-chlorochromen-2-one (1439370-55-4) + 1-amino-1-phenyl-propan-2-on hydrochloride (3904-16-3) → 4-((2-oxo-1-phenylpropyl)amino)-3-benzoyl-7-dimethylaminocoumarin (1439370-56-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In 1,2-dichloro-ethane; at 80 ℃; for 0.5h; Microwave irradiation;

DOI:10.1021/ol401138q

Reference yield: 98.0%

4-((2-oxo-1-phenylpropyl)amino)-3-benzoyl-7-dimethylaminocoumarin (1439370-56-5) → 7-(dimethylamino)-3-phenyl-2-phenylchromeno[4,3-b]pyrrol-4(1H)-one (1439370-59-8)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; for 0.5h; Reflux;

DOI:10.1021/ol401138q

upstream raw materials:

3-benzoyl-7-N,N-dimethylamino-4-chlorochromen-2-one

1-amino-1-phenyl-propan-2-on hydrochloride

Downstream raw materials:

7-(dimethylamino)-3-phenyl-2-phenylchromeno[4,3-b]pyrrol-4(1H)-one