3-(4-methoxycarbonylbenzyl)oxindole

Base Information

• Chemical Name: 3-(4-methoxycarbonylbenzyl)oxindole
• CAS No.: 1105512-82-0
• Molecular Formula: C₁₇H₁₅NO₃
• Molecular Weight: 281.311
• Mol file: 1105512-82-0.mol

Synonyms:3-(4-methoxycarbonylbenzyl)oxindole

Chemical Property of 3-(4-methoxycarbonylbenzyl)oxindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 3-(4-methoxycarbonylbenzyl)oxindole

There total 3 articles about 3-(4-methoxycarbonylbenzyl)oxindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

methyl (2E)-2-(2-nitrophenyl)-3-(4-methoxycarbonylphenyl)acrylate (1231755-78-4) → 3-(4-methoxycarbonylbenzyl)oxindole (1105512-82-0)

Guidance literature:

With tetrafluoroboric acid; 5%-palladium/activated carbon; hydrogen; In methanol; water; at 40 ℃; for 12h;

DOI:10.1016/j.tetlet.2009.06.084

Reference yield: 81.0%

4-(methoxycarbonyl)benzenediazonium tetrafluoroborate + methyl α-(2-nitrophenyl)acrylate (494836-60-1) → 3-(4-methoxycarbonylbenzyl)oxindole (1105512-82-0)

Guidance literature:

4-(methoxycarbonyl)benzenediazonium tetrafluoroborate; methyl α-(2-nitrophenyl)acrylate; With palladium diacetate; In methanol; at 40 ℃;

With hydrogen; pyrographite; In methanol; at 40 ℃; for 24h;

DOI:10.1016/j.tetlet.2009.06.084

Reference yield: 75.0%

methyl 2-(2-nitrophenyl)-3-(4-methoxycarbonylphenyl)acrylate (1105512-95-5) → 3-(4-methoxycarbonylbenzyl)oxindole (1105512-82-0)

Guidance literature:

With hydrogen; palladium diacetate; pyrographite; In methanol; at 40 ℃; for 24h;

DOI:10.1021/jo802467s

upstream raw materials:

methyl 2-(2-nitrophenyl)-3-(4-methoxycarbonylphenyl)acrylate

methyl (2E)-2-(2-nitrophenyl)-3-(4-methoxycarbonylphenyl)acrylate

methyl α-(2-nitrophenyl)acrylate