(1R,2R,3R,4R)-3-methoxy-6-(7-methyl-3-methylene-oct-6-en-1-ynyl)-cyclohex-5-ene-1,2,4-triol

Base Information

• Chemical Name: (1R,2R,3R,4R)-3-methoxy-6-(7-methyl-3-methylene-oct-6-en-1-ynyl)-cyclohex-5-ene-1,2,4-triol
• CAS No.: 1380508-49-5
• Molecular Formula: C₁₇H₂₄O₄
• Molecular Weight: 292.375
• Mol file: 1380508-49-5.mol

Synonyms:(1R,2R,3R,4R)-3-methoxy-6-(7-methyl-3-methylene-oct-6-en-1-ynyl)-cyclohex-5-ene-1,2,4-triol

Chemical Property of (1R,2R,3R,4R)-3-methoxy-6-(7-methyl-3-methylene-oct-6-en-1-ynyl)-cyclohex-5-ene-1,2,4-triol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2R,3R,4R)-3-methoxy-6-(7-methyl-3-methylene-oct-6-en-1-ynyl)-cyclohex-5-ene-1,2,4-triol

There total 9 articles about (1R,2R,3R,4R)-3-methoxy-6-(7-methyl-3-methylene-oct-6-en-1-ynyl)-cyclohex-5-ene-1,2,4-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(1S,2R,3R,4R)-6-iodo-3-methoxycyclohex-5-ene-1,2,4-triol + 2-(4-methyl-3-pentenyl)-1-buten-3-yne (36602-33-2) → (1R,2R,3R,4R)-3-methoxy-6-(7-methyl-3-methylene-oct-6-en-1-ynyl)-cyclohex-5-ene-1,2,4-triol (1380508-49-5)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In diethylamine; at 18 ℃; for 3h; Inert atmosphere;

DOI:10.1021/np4002866

Reference yield: 79.0%

1,2-O,O′-isopropylidenephomentrioloxin (1448608-17-0) → (1R,2R,3R,4R)-3-methoxy-6-(7-methyl-3-methylene-oct-6-en-1-ynyl)-cyclohex-5-ene-1,2,4-triol (1380508-49-5)

Guidance literature:

With water; acetic acid; at 70 ℃; for 5h;

DOI:10.1021/np4002866

Reference yield: 57.0%

C29H48O4Si (1448608-18-1) → (1R,2R,3R,4R)-3-methoxy-6-(7-methyl-3-methylene-oct-6-en-1-ynyl)-cyclohex-5-ene-1,2,4-triol (1380508-49-5)

Guidance literature:

With water; acetic acid; at 70 ℃; for 18h;

DOI:10.1021/np4002866

upstream raw materials:

2-(4-methyl-3-pentenyl)-1-buten-3-yne

1,2-O,O′-isopropylidenephomentrioloxin

C₂₉H₄₈O₄Si

cis-(1S,2S)-1,2-dihydroxy-3-iodocyclohexa-3,5-diene

Downstream raw materials:

1,2,4-O,O′,O″-triacetylphomentrioloxin

1,2,4-tri-O-acetylphomentrioloxin