(2R,3S)?isocitric acid trimethylester

Base Information

• Chemical Name: (2R,3S)?isocitric acid trimethylester
• CAS No.: 284679-33-0
• Molecular Formula: C₉H₁₄O₇
• Molecular Weight: 234.206

Synonyms:(2R,3S)?isocitric acid trimethylester

Chemical Property of (2R,3S)?isocitric acid trimethylester

Chemical Property:

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Technology Process of (2R,3S)?isocitric acid trimethylester

There total 1 articles about (2R,3S)?isocitric acid trimethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-dimethyl malate (70681-41-3) → (2R,3S)?isocitric acid trimethylester (284679-33-0)

Guidance literature:

Multi-step reaction with 6 steps

1: LDA

2: EtNiPr₂

3: O₃ / CH₂Cl₂; methanol

With ozone; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In methanol; dichloromethane; 1: allylation / 2: Etherification / 3: ozonolysis / 4: Jones oxidation / 5: Methylation / 6: deprotection;

DOI:10.1016/S0040-4039(00)00316-6

upstream raw materials:

(R)-dimethyl malate

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