C₃₃H₃₉NO₄Si

Base Information

• Chemical Name: C₃₃H₃₉NO₄Si
• CAS No.: 1256603-69-6
• Molecular Formula: C₃₃H₃₉NO₄Si
• Molecular Weight: 541.762
• Mol file: 1256603-69-6.mol

Synonyms:C₃₃H₃₉NO₄Si

Chemical Property of C₃₃H₃₉NO₄Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₃₉NO₄Si

There total 19 articles about C₃₃H₃₉NO₄Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

C17H21NO4 (1256603-68-5) + tert-butylchlorodiphenylsilane (58479-61-1) → C33H39NO4Si (1256603-69-6)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 18 ℃; for 18h; Inert atmosphere;

DOI:10.1071/CH10201

Reference yield:

C11H15BrO5 (1256603-54-9) → C33H39NO4Si (1256603-69-6)

Guidance literature:

Multi-step reaction with 14 steps

1.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 18 h / 18 °C / Inert atmosphere

2.1: potassium carbonate / methanol / 1 h / 18 °C

3.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; benzene / 18 °C / Inert atmosphere; Reflux

4.1: di-isopropyl azodicarboxylate; triphenylphosphine / toluene / 18 h / 18 °C

5.1: potassium carbonate / methanol / 1 h / 18 °C

6.1: toluene / 168 h / Reflux

7.1: bromine / toluene / 18 h / 18 °C

7.2: 2 h

8.1: palladium 10% on activated carbon; hydrogen; potassium carbonate / methanol / 18 h / 18 °C

9.1: dmap / pyridine / 2 h / 18 °C

10.1: acetic acid / water / 20 h / 18 °C

11.1: dmap / dichloromethane / 1 h / 0 °C / Inert atmosphere

12.1: phosphorous acid trimethyl ester / toluene / 18 h / Reflux

13.1: potassium carbonate / methanol / 1 h / 18 °C

14.1: 1H-imidazole / dichloromethane / 18 h / 18 °C / Inert atmosphere

With 1H-imidazole; dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; di-isopropyl azodicarboxylate; palladium 10% on activated carbon; hydrogen; bromine; sodium carbonate; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; triphenylphosphine; phosphorous acid trimethyl ester; In pyridine; methanol; dichloromethane; water; toluene; benzene; 3.1: Suzuki-Miyaura cross-coupling / 4.1: Mitsunobu reaction / 12.1: Corey-Winter olefination reaction;

DOI:10.1071/CH10201

Reference yield:

C11H17BrO5 (1256603-56-1) → C33H39NO4Si (1256603-69-6)

Guidance literature:

Multi-step reaction with 12 steps

1.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; benzene / 18 °C / Inert atmosphere; Reflux

2.1: di-isopropyl azodicarboxylate; triphenylphosphine / toluene / 18 h / 18 °C

3.1: potassium carbonate / methanol / 1 h / 18 °C

4.1: toluene / 168 h / Reflux

5.1: bromine / toluene / 18 h / 18 °C

5.2: 2 h

6.1: palladium 10% on activated carbon; hydrogen; potassium carbonate / methanol / 18 h / 18 °C

7.1: dmap / pyridine / 2 h / 18 °C

8.1: acetic acid / water / 20 h / 18 °C

9.1: dmap / dichloromethane / 1 h / 0 °C / Inert atmosphere

10.1: phosphorous acid trimethyl ester / toluene / 18 h / Reflux

11.1: potassium carbonate / methanol / 1 h / 18 °C

12.1: 1H-imidazole / dichloromethane / 18 h / 18 °C / Inert atmosphere

With 1H-imidazole; dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; di-isopropyl azodicarboxylate; palladium 10% on activated carbon; hydrogen; bromine; sodium carbonate; potassium carbonate; acetic acid; triphenylphosphine; phosphorous acid trimethyl ester; In pyridine; methanol; dichloromethane; water; toluene; benzene; 1.1: Suzuki-Miyaura cross-coupling / 2.1: Mitsunobu reaction / 10.1: Corey-Winter olefination reaction;

DOI:10.1071/CH10201

upstream raw materials:

C₂₀H₂₅Br₂NO₆

C₂₀H₂₇NO₆

C₂₂H₂₉NO₇

C₂₀H₂₃NO₇S

Downstream raw materials:

C₃₁H₃₆O₄Si

C₃₂H₃₇NO₄Si

C₃₁H₃₄O₄Si