Toluene-4-sulfonic acid 4-(toluene-4-sulfonylamino)-cyclohexyl ester

Base Information

• Chemical Name: Toluene-4-sulfonic acid 4-(toluene-4-sulfonylamino)-cyclohexyl ester
• CAS No.: 204692-06-8
• Molecular Formula: C₂₀H₂₅NO₅S₂
• Molecular Weight: 423.554
• Mol file: 204692-06-8.mol

Synonyms:Toluene-4-sulfonic acid 4-(toluene-4-sulfonylamino)-cyclohexyl ester

Chemical Property of Toluene-4-sulfonic acid 4-(toluene-4-sulfonylamino)-cyclohexyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of Toluene-4-sulfonic acid 4-(toluene-4-sulfonylamino)-cyclohexyl ester

There total 1 articles about Toluene-4-sulfonic acid 4-(toluene-4-sulfonylamino)-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

trans-4-hydroxycyclohexylamine (27489-62-9) + p-toluenesulfonyl chloride (98-59-9) → Toluene-4-sulfonic acid 4-(toluene-4-sulfonylamino)-cyclohexyl ester (204692-06-8)

Guidance literature:

DOI:10.1016/S0040-4039(97)10876-0

Reference yield: 89.0%

Toluene-4-sulfonic acid 4-(toluene-4-sulfonylamino)-cyclohexyl ester (204692-06-8) → 7-(Toluene-4-sulfonyl)-7-aza-bicyclo[2.2.1]heptane

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; benzene;

DOI:10.1016/S0040-4039(97)10876-0

Reference yield:

Toluene-4-sulfonic acid 4-(toluene-4-sulfonylamino)-cyclohexyl ester (204692-06-8) → [4-(7-Aza-bicyclo[2.2.1]heptane-7-sulfonyl)-phenyl]-methanol

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / t-BuOK / dimethylformamide; benzene

2: 34 percent / Beauveria bassiana (ATCC 7159), corn steep liquor, D-glucose, pH 5.0 / H₂O; dimethylformamide

With D-glucose; Beauveria bassiana (ATCC 7159); corn steep liquor; potassium tert-butylate; In water; N,N-dimethyl-formamide; benzene;

DOI:10.1016/S0040-4039(97)10876-0

upstream raw materials:

trans-4-hydroxycyclohexylamine

p-toluenesulfonyl chloride