4-(4-[3-amino-2-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide

Base Information

• Chemical Name: 4-(4-[3-amino-2-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide
• CAS No.: 1418128-36-5
• Molecular Formula: C₃₇H₄₂N₆O₂Si
• Molecular Weight: 630.865

Synonyms:4-(4-[3-amino-2-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide

Chemical Property of 4-(4-[3-amino-2-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-[3-amino-2-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide

There total 1 articles about 4-(4-[3-amino-2-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-(4-[3-amino-2-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide (1418128-36-5)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In propan-1-ol; water; at 100 ℃; for 16h;

Reference yield:

4-(4-[3-amino-2-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide (1418128-36-5) + 2-fluoro-4-(1-hydroxy-1-methyl-ethyl)-benzoic acid (1418128-37-6) → 4-(4-[2-(tert-butyl-diphenyl-silanyloxymethyl)-3-[2-fluoro-4-(1-hydroxy-1-methyl-ethyl)-benzoylamino]-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide (1418128-38-7)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 22h;

Downstream raw materials:

4-(4-[2-(tert-butyl-diphenyl-silanyloxymethyl)-3-[2-fluoro-4-(1-hydroxy-1-methyl-ethyl)-benzoylamino]-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1418128-36-5 4-(4-[3-amino-2-(tert-butyl-diphenyl-silanyloxymethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid dimethylamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send