1,5-bis(3,4-dimethoxyphenyl)pentane

Base Information

• Chemical Name: 1,5-bis(3,4-dimethoxyphenyl)pentane
• CAS No.: 51487-59-3
• Molecular Formula: C₂₁H₂₈O₄
• Molecular Weight: 344.451
• Mol file: 51487-59-3.mol

Synonyms:1,5-bis(3,4-dimethoxyphenyl)pentane

Chemical Property of 1,5-bis(3,4-dimethoxyphenyl)pentane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,5-bis(3,4-dimethoxyphenyl)pentane

There total 4 articles about 1,5-bis(3,4-dimethoxyphenyl)pentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1,5-bis(3,4-dimethoxyphenyl)-3-pentanone (68081-12-9) → 1,5-bis(3,4-dimethoxyphenyl)pentane (51487-59-3)

Guidance literature:

With hydrazine hydrate; potassium hydroxide; at 105 ℃; for 5h; Inert atmosphere;

DOI:10.1016/j.ejmech.2019.111910

Reference yield:

3,4-dimethoxy-benzaldehyde (120-14-9) → 1,5-bis(3,4-dimethoxyphenyl)pentane (51487-59-3)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide / ethanol / 4 h / 22 °C / Inert atmosphere

2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 4 h / 22 °C / 2327.23 Torr / Inert atmosphere

3: zinc amalgam; hydrogenchloride / water; toluene / 35 h / Inert atmosphere; Reflux

With hydrogenchloride; palladium 10% on activated carbon; zinc amalgam; hydrogen; sodium hydroxide; In ethanol; water; ethyl acetate; toluene;

DOI:10.1002/anie.201609695

Reference yield:

1,5-bis(3,4-dimethoxyphenyl)-1,4-pentadien-3-one (38552-39-5) → 1,5-bis(3,4-dimethoxyphenyl)pentane (51487-59-3)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 4 h / 22 °C / 2327.23 Torr / Inert atmosphere

2: zinc amalgam; hydrogenchloride / water; toluene / 35 h / Inert atmosphere; Reflux

With hydrogenchloride; palladium 10% on activated carbon; zinc amalgam; hydrogen; In water; ethyl acetate; toluene;

DOI:10.1002/anie.201609695

upstream raw materials:

1,5-bis(3,4-dimethoxyphenyl)-3-pentanone

1,5-bis(3,4-dimethoxyphenyl)-1,4-pentadien-3-one

3,4-dimethoxy-benzaldehyde

Downstream raw materials:

1,5-bis(6-bromo-3,4-dimethoxyphenyl)pentane

5-(3,4-Dimethoxy-phenyl)-2,3-dimethoxy-6,7,8,9-tetrahydro-5H-benzocycloheptene

4,4’-(pentane-1,5-diyl)bis(benzene-1,2-diol)