5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-benzylidene-, ethyl ester

Base Information

• Chemical Name: 5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-benzylidene-, ethyl ester
• CAS No.: 138722-52-8
• Molecular Formula: C₂₉H₃₂N₂O₄
• Molecular Weight: 472.584

Synonyms:5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-benzylidene-, ethyl ester

Chemical Property of 5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-benzylidene-, ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-benzylidene-, ethyl ester

There total 8 articles about 5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-benzylidene-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

2-benzylidene-7-(hydroxymethylidene)cycloheptanone (138722-50-6) + 3-<<(3,4-dimethoxyphenyl)methyl>amino>-3-aminopropenoic acid, ethyl ester (138722-51-7) → 5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-benzylidene-, ethyl ester (138722-52-8)

Guidance literature:

In tetrahydrofuran; for 20h; Ambient temperature;

Reference yield: 61.0%

2-benzylidene-7-(hydroxymethylidene)cycloheptanone (138722-50-6) + 3-<<(3,4-dimethoxyphenyl)methyl>amino>-3-aminopropenoic acid (138722-51-7) → 5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-benzylidene-, ethyl ester (138722-52-8)

Guidance literature:

DOI:10.1021/ja00031a065

Reference yield:

(E)-2-benzylidenecycloheptanone (88356-04-1) → 5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-benzylidene-, ethyl ester (138722-52-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 94 percent / dimethylformamide / 60 h / Heating

2: 97 percent / 2 N aq. HCl / 2.5 h

3: 61 percent / tetrahydrofuran / 20 h / Ambient temperature

With hydrogenchloride; In tetrahydrofuran; N,N-dimethyl-formamide;

upstream raw materials:

2-benzylidene-7-(hydroxymethylidene)cycloheptanone

3-<<(3,4-dimethoxyphenyl)methyl>amino>-3-aminopropenoic acid

3-<<(3,4-dimethoxyphenyl)methyl>amino>-3-aminopropenoic acid, ethyl ester

(E)-2-benzylidenecycloheptanone

Downstream raw materials:

5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-oxo-, ethyl ester

5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7-dihydro-9-(1-pyrrolidinyl), ethyl ester

bispyrido<3',2':6,7>cyclohepta<1,2-b:2',1'-e>pyridine-3,8,13-tricarboxylic acid, 2,14-bis<<(3,4-dimethoxyphenyl)methyl>amino>-5,6,7,9,10,11-hexahydro-, triethyl ester

α-bis-<2-<<(3,4-dimethoxyphenyl)methyl>amino>-3-(ethoxycarbonyl)-6,7,8,9-tetrahydro-9-oxo-8-(5H)-pyridocycloheptyl>acetic acid, ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 138722-52-8 5H-cycloheptapyridine-3-carboxylic acid, 2-<<(3,4-dimethoxyphenyl)methyl>amino>-6,7,8,9-tetrahydro-9-benzylidene-, ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send