2-<2'-(N,N-dimethylamino)ethoxy>-5-ter-butyl-3-<4-pentenyl>-1,4-cyclohexadiene

Base Information

• Chemical Name: 2-<2'-(N,N-dimethylamino)ethoxy>-5-ter-butyl-3-<4-pentenyl>-1,4-cyclohexadiene
• CAS No.: 148270-94-4
• Molecular Formula: C₁₉H₃₃NO
• Molecular Weight: 291.477
• Mol file: 148270-94-4.mol

Synonyms:2-<2'-(N,N-dimethylamino)ethoxy>-5-ter-butyl-3-<4-pentenyl>-1,4-cyclohexadiene

Chemical Property of 2-<2'-(N,N-dimethylamino)ethoxy>-5-ter-butyl-3-<4-pentenyl>-1,4-cyclohexadiene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-<2'-(N,N-dimethylamino)ethoxy>-5-ter-butyl-3-<4-pentenyl>-1,4-cyclohexadiene

There total 1 articles about 2-<2'-(N,N-dimethylamino)ethoxy>-5-ter-butyl-3-<4-pentenyl>-1,4-cyclohexadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromopentene (1119-51-3) + 1-<2'-(N,N-dimethylamino)ethoxy>-4-ter-butyl-1,4-cyclohexadiene (148270-93-3) → 2-<2'-(N,N-dimethylamino)ethoxy>-5-ter-butyl-3-<4-pentenyl>-1,4-cyclohexadiene (148270-94-4)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) THF, hexane, hexamethylphosphamide, -70 deg C, 10 min, 2.) + THF, a) -70 deg C, 20 min, b) room temperature, 3 h;

DOI:10.1016/S0040-4020(01)80336-7

Reference yield: 67.0%

2-<2'-(N,N-dimethylamino)ethoxy>-5-ter-butyl-3-<4-pentenyl>-1,4-cyclohexadiene (148270-94-4) → 4-ter-butyl-2-<4-pentenyl>-2-cyclohexen-1-one (111280-41-2)

Guidance literature:

With hydrogenchloride; In acetone; at 50 ℃; for 2h;

DOI:10.1016/S0040-4020(01)80336-7

Reference yield:

2-<2'-(N,N-dimethylamino)ethoxy>-5-ter-butyl-3-<4-pentenyl>-1,4-cyclohexadiene (148270-94-4) → (3aS,4aR,5S,8aR)-7-[1-(4-Bromo-phenyl)-meth-(E)-ylidene]-5-tert-butyl-octahydro-cyclopenta[1,4]cyclobuta[1,2]benzen-8-one

Guidance literature:

Multi-step reaction with 3 steps

1: 67 percent / 2N hydrochloric acid / acetone / 2 h / 50 °C

2: cyclohexane / 4 h / Irradiation

With hydrogenchloride; In cyclohexane; acetone;

DOI:10.1016/S0040-4020(01)80336-7

upstream raw materials:

bromopentene

1-<2'-(N,N-dimethylamino)ethoxy>-4-ter-butyl-1,4-cyclohexadiene

Downstream raw materials:

4-ter-butyl-2-<4-pentenyl>-2-cyclohexen-1-one