dimethyl 2-(but-2-en-1-yl)-2-(3-phenylprop-2-yn-1-yl)malonate

Base Information

• Chemical Name: dimethyl 2-(but-2-en-1-yl)-2-(3-phenylprop-2-yn-1-yl)malonate
• CAS No.: 960132-96-1
• Molecular Formula: C₁₈H₂₀O₄
• Molecular Weight: 300.354
• Mol file: 960132-96-1.mol

Synonyms:dimethyl 2-(but-2-en-1-yl)-2-(3-phenylprop-2-yn-1-yl)malonate

Chemical Property of dimethyl 2-(but-2-en-1-yl)-2-(3-phenylprop-2-yn-1-yl)malonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of dimethyl 2-(but-2-en-1-yl)-2-(3-phenylprop-2-yn-1-yl)malonate

There total 1 articles about dimethyl 2-(but-2-en-1-yl)-2-(3-phenylprop-2-yn-1-yl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

iodobenzene (591-50-4) + 2-but-2-enyl-2-prop-2-ynyl-malonic acid dimethyl ester (113704-38-4) → dimethyl 2-(but-2-en-1-yl)-2-(3-phenylprop-2-yn-1-yl)malonate (960132-96-1) + Methyl 2-(3-phenylprop-2-ynyl)-2-[(E)-but-2-enyl]propanedioate (379228-66-7)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 20 ℃; for 12h; Overall yield = 75 percent; Overall yield = 1 g;

DOI:10.1002/chem.201903405

Reference yield: 84.0%

dimethyl 2-(but-2-en-1-yl)-2-(3-phenylprop-2-yn-1-yl)malonate (960132-96-1) → (+)-(E)-dimethyl 3-benzylidene-4-vinylcyclopentane-1,1-dicarboxylate

Guidance literature:

With silver hexafluoroantimonate; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); chloro(1,5-cyclooctadiene)rhodium(I) dimer; In 1,2-dichloro-ethane; at 20 ℃;

DOI:10.1039/b712396e

upstream raw materials:

iodobenzene

2-but-2-enyl-2-prop-2-ynyl-malonic acid dimethyl ester