Technology Process of C58H70N7O11(1+)
There total 9 articles about C58H70N7O11(1+) which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
8-hydroxyjulolidine; [(2-{(2-[2-bis(methoxycarbonylmethyl)amino-5-methylphenoxy]-7-azidooctan-2-yl)oxy}-4-formylphenyl)(methoxycarbonylmethyl)amino]acetic acid methyl ester;
With
toluene-4-sulfonic acid;
In
propionic acid;
for 18h;
With
chloranil;
In
dichloromethane; propionic acid;
for 4h;
DOI:10.1021/ja304018d
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 24 h / Reflux
2.1: trichlorophosphate; N,N-dimethyl-formamide / 20.5 h / 20 - 45 °C
3.1: hydrogen bromide / dichloromethane; acetic acid / 1 h / 20 °C
4.1: sodium azide / N,N-dimethyl-formamide / 2 h / 100 °C
5.1: toluene-4-sulfonic acid / propionic acid / 18 h
5.2: 4 h
With
sodium azide; hydrogen bromide; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; trichlorophosphate;
In
dichloromethane; acetic acid; propionic acid; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja304018d
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: potassium hydroxide / water; dichloromethane
2.1: N,N-dimethyl-formamide / 18 h / 90 °C / Inert atmosphere
3.1: tin(II) chloride dihdyrate; hydrogenchloride / water; ethanol / 1.5 h / 78 °C
4.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 24 h / Reflux
5.1: trichlorophosphate; N,N-dimethyl-formamide / 20.5 h / 20 - 45 °C
6.1: hydrogen bromide / dichloromethane; acetic acid / 1 h / 20 °C
7.1: sodium azide / N,N-dimethyl-formamide / 2 h / 100 °C
8.1: toluene-4-sulfonic acid / propionic acid / 18 h
8.2: 4 h
With
hydrogenchloride; sodium azide; tin(II) chloride dihdyrate; hydrogen bromide; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; potassium hydroxide; trichlorophosphate;
In
ethanol; dichloromethane; water; acetic acid; propionic acid; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja304018d