(R)-4-(2-amino-4,5-dimethyl-phenylcarbamoyl)-2-t-butoxycarbonylaminobutyric acid benzyl ester

Base Information

Chemical Name:(R)-4-(2-amino-4,5-dimethyl-phenylcarbamoyl)-2-t-butoxycarbonylaminobutyric acid benzyl ester
CAS No.:862403-41-6
Molecular Formula:C₂₅H₃₃N₃O₅
Molecular Weight:455.554
Hs Code.:

Synonyms:(R)-4-(2-amino-4,5-dimethyl-phenylcarbamoyl)-2-t-butoxycarbonylaminobutyric acid benzyl ester

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Chemical Property of (R)-4-(2-amino-4,5-dimethyl-phenylcarbamoyl)-2-t-butoxycarbonylaminobutyric acid benzyl ester

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Technology Process of (R)-4-(2-amino-4,5-dimethyl-phenylcarbamoyl)-2-t-butoxycarbonylaminobutyric acid benzyl ester

There total 1 articles about (R)-4-(2-amino-4,5-dimethyl-phenylcarbamoyl)-2-t-butoxycarbonylaminobutyric acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 34404-30-3
N-(tert-butoxycarbonyl)-D-glutamic acid 1-benzyl ester

: 3171-45-7
4,5-dimethyl-1,2-phenylenediamine

: 862403-41-6
(R)-4-(2-amino-4,5-dimethyl-phenylcarbamoyl)-2-t-butoxycarbonylaminobutyric acid benzyl ester

Guidance literature:: N-(tert-butoxycarbonyl)-D-glutamic acid 1-benzyl ester; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In chloroform; at 20 ℃; for 0.0833333h;

4,5-dimethyl-1,2-phenylenediamine; In chloroform; at 20 ℃;

Reference yield:

: 862403-41-6
(R)-4-(2-amino-4,5-dimethyl-phenylcarbamoyl)-2-t-butoxycarbonylaminobutyric acid benzyl ester

: 2043-61-0
cyclohexanecarbaldehyde

: C₃₂H₄₅N₃O₅

Guidance literature:: (R)-4-(2-amino-4,5-dimethyl-phenylcarbamoyl)-2-t-butoxycarbonylaminobutyric acid benzyl ester; cyclohexanecarbaldehyde; In acetone; at 20 ℃; for 1h;

With sodium tris(acetoxy)borohydride; In acetone; at 20 ℃; for 3h;

With sodium hydroxide; water; In chloroform; acetone;