3-[(2S,3R)-2-(4-benzyloxy-phenyl)-1-(4-fluorophenyl)-4-oxo-azetidin-3-yl]-propionic acid benzyl ester

Base Information

Chemical Name:3-[(2S,3R)-2-(4-benzyloxy-phenyl)-1-(4-fluorophenyl)-4-oxo-azetidin-3-yl]-propionic acid benzyl ester
CAS No.:1046809-85-1
Molecular Formula:C₃₂H₂₈FNO₄
Molecular Weight:509.577
Hs Code.:

Synonyms:3-[(2S,3R)-2-(4-benzyloxy-phenyl)-1-(4-fluorophenyl)-4-oxo-azetidin-3-yl]-propionic acid benzyl ester

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Chemical Property of 3-[(2S,3R)-2-(4-benzyloxy-phenyl)-1-(4-fluorophenyl)-4-oxo-azetidin-3-yl]-propionic acid benzyl ester

Chemical Property:

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MSDS Files:: SDS file from LookChem

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Technology Process of 3-[(2S,3R)-2-(4-benzyloxy-phenyl)-1-(4-fluorophenyl)-4-oxo-azetidin-3-yl]-propionic acid benzyl ester

There total 1 articles about 3-[(2S,3R)-2-(4-benzyloxy-phenyl)-1-(4-fluorophenyl)-4-oxo-azetidin-3-yl]-propionic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1046809-84-0
(R)-4-[(4-benzyloxy-phenyl)-(4-fluoro-phenylamino)-methyl]-5-oxo-5-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)pentanoic acid benzyl ester

: 1046809-85-1
3-[(2S,3R)-2-(4-benzyloxy-phenyl)-1-(4-fluorophenyl)-4-oxo-azetidin-3-yl]-propionic acid benzyl ester

Guidance literature:: With N,O-bis-(trimethylsilyl)-acetamide; tetrabutyl ammonium fluoride; In tert-butyl methyl ether; at 20 - 42 ℃; for 0.166667h;

Reference yield:

: 1046809-85-1
3-[(2S,3R)-2-(4-benzyloxy-phenyl)-1-(4-fluorophenyl)-4-oxo-azetidin-3-yl]-propionic acid benzyl ester

: 204589-82-2
(3R,4S)-1-(4-fluorophenyl)-3-(3-hydroxy-3-oxopropyl)-4-(4-benzyloxyphenyl)-2-azetidinone

Guidance literature:: 3-[(2S,3R)-2-(4-benzyloxy-phenyl)-1-(4-fluorophenyl)-4-oxo-azetidin-3-yl]-propionic acid benzyl ester; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃;

With hydrogenchloride; water; In ethyl acetate;