2-(2-aminophenyl)-3-nitrosoindole

Base Information

• Chemical Name: 2-(2-aminophenyl)-3-nitrosoindole
• CAS No.: 238398-51-1
• Molecular Formula: C₁₄H₁₁N₃O
• Molecular Weight: 237.261
• Mol file: 238398-51-1.mol

Synonyms:2-(2-aminophenyl)-3-nitrosoindole

Chemical Property of 2-(2-aminophenyl)-3-nitrosoindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-aminophenyl)-3-nitrosoindole

There total 3 articles about 2-(2-aminophenyl)-3-nitrosoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-(2-acetylaminophenyl)-3-nitrosoindole (238398-45-3) → 2-(2-aminophenyl)-3-nitrosoindole (238398-51-1)

Guidance literature:

With potassium hydroxide; In ethanol; for 2h; Heating;

DOI:10.1021/jm9806087

Reference yield:

2-(2-aminophenyl)-1H-indole (32566-01-1) → 2-(2-aminophenyl)-3-nitrosoindole (238398-51-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 98 percent / 2 h / Ambient temperature

2: 97 percent / aq. NaNO₂, AcOH / 1 h / 0 - 5 °C

3: 90 percent / aq. KOH / ethanol / 2 h / Heating

With potassium hydroxide; acetic acid; sodium nitrite; In ethanol;

DOI:10.1021/jm9806087

Reference yield:

N-[2-(1H-indol-2-yl)phenyl]acetamide (58995-86-1) → 2-(2-aminophenyl)-3-nitrosoindole (238398-51-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / aq. NaNO₂, AcOH / 1 h / 0 - 5 °C

2: 90 percent / aq. KOH / ethanol / 2 h / Heating

With potassium hydroxide; acetic acid; sodium nitrite; In ethanol;

DOI:10.1021/jm9806087

upstream raw materials:

2-(2-acetylaminophenyl)-3-nitrosoindole

2-(2-aminophenyl)-1H-indole

N-[2-(1H-indol-2-yl)phenyl]acetamide