4-(5-(4-chloro-phenyl)-3-iodo-2-methyl-pyrrol-1-yl)-benzenesulfonamide

Base Information

• Chemical Name: 4-(5-(4-chloro-phenyl)-3-iodo-2-methyl-pyrrol-1-yl)-benzenesulfonamide
• CAS No.: 1000280-36-3
• Molecular Formula: C₁₇H₁₄ClIN₂O₂S
• Molecular Weight: 472.734

Synonyms:4-(5-(4-chloro-phenyl)-3-iodo-2-methyl-pyrrol-1-yl)-benzenesulfonamide

Chemical Property of 4-(5-(4-chloro-phenyl)-3-iodo-2-methyl-pyrrol-1-yl)-benzenesulfonamide

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Technology Process of 4-(5-(4-chloro-phenyl)-3-iodo-2-methyl-pyrrol-1-yl)-benzenesulfonamide

There total 1 articles about 4-(5-(4-chloro-phenyl)-3-iodo-2-methyl-pyrrol-1-yl)-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

disodium 5-(4-chloro-phenyl)-2-methyl-1-(4-sulfamoyl-phenyl)-1H-pyrrole-3-carboxylate → 4-(5-(4-chloro-phenyl)-3-iodo-2-methyl-pyrrol-1-yl)-benzenesulfonamide (1000280-36-3) + 4-(2-(4-chloro-phenyl)-3.4-diiodo-5-methyl-pyrrol-1-yl)-benzenesulfonamide (1000280-37-4)

Guidance literature:

With iodine; In water; N,N-dimethyl-formamide; at 0 - 20 ℃; for 1.25h;

Reference yield:

4-(5-(4-chloro-phenyl)-3-iodo-2-methyl-pyrrol-1-yl)-benzenesulfonamide (1000280-36-3) + p-hydroxymethylphenylboronic acid (59016-93-2) → 4-[5-(4-chloro-phenyl)-3-(4-hydroxymethyl-phenyl)-2-methyl-pyrrol-1-yl]-benzenesulfonamide (1000280-38-5)

Guidance literature:

With caesium carbonate; palladium diacetate; In ethanol; at 90 - 100 ℃; for 0.416667h; Microwave irradiation;

Reference yield:

4-(5-(4-chloro-phenyl)-3-iodo-2-methyl-pyrrol-1-yl)-benzenesulfonamide (1000280-36-3) + benzofuran-2-boronic acid (98437-24-2) → 4-[3-benzofuran-2-yl-5-(4-chloro-phenyl)-2-methyl-pyrrol-1-yl]-benzenesulfonamide (1000280-39-6)

Guidance literature:

With caesium carbonate; palladium diacetate; In ethanol; at 120 ℃; for 0.25h; Microwave irradiation;

Downstream raw materials:

4-[5-(4-chloro-phenyl)-3-(4-hydroxymethyl-phenyl)-2-methyl-pyrrol-1-yl]-benzenesulfonamide

4-[3-benzofuran-2-yl-5-(4-chloro-phenyl)-2-methyl-pyrrol-1-yl]-benzenesulfonamide

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