Technology Process of 2-(2-azidoethyl)-N-benzyl-N-(2-iodophenyl)acrylamide
There total 7 articles about 2-(2-azidoethyl)-N-benzyl-N-(2-iodophenyl)acrylamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
diphenylphosphoranyl azide; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran;
at 20 ℃;
for 24h;
DOI:10.1039/b208114h
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 96 percent / SOCl2 / diethyl ether / 0.25 h / Heating
2: 94 percent / Et3N / benzene / 2 h
3: 84 percent / LiCl; NaBH4 / tetrahydrofuran; ethanol / 16 h / 20 °C
4: 70 percent / PPh3; DEAD; diphenylphosphoryl azide / tetrahydrofuran / 24 h / 20 °C
With
sodium tetrahydroborate; thionyl chloride; diphenylphosphoranyl azide; triethylamine; triphenylphosphine; lithium chloride; diethylazodicarboxylate;
In
tetrahydrofuran; diethyl ether; ethanol; benzene;
DOI:10.1039/b208114h
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 92 percent / ZnCl2; NaCNBH3 / CH2Cl2 / 2 h / Heating
2: 94 percent / Et3N / benzene / 2 h
3: 84 percent / LiCl; NaBH4 / tetrahydrofuran; ethanol / 16 h / 20 °C
4: 70 percent / PPh3; DEAD; diphenylphosphoryl azide / tetrahydrofuran / 24 h / 20 °C
With
sodium tetrahydroborate; diphenylphosphoranyl azide; sodium cyanoborohydride; triethylamine; triphenylphosphine; lithium chloride; zinc(II) chloride; diethylazodicarboxylate;
In
tetrahydrofuran; ethanol; dichloromethane; benzene;
DOI:10.1039/b208114h
