5-(pent-4-en-1-ylthio)-1-phenyl-1H-tetrazole

Base Information

• Chemical Name: 5-(pent-4-en-1-ylthio)-1-phenyl-1H-tetrazole
• CAS No.: 1019646-01-5
• Molecular Formula: C₁₂H₁₄N₄S
• Molecular Weight: 246.336
• Mol file: 1019646-01-5.mol

Synonyms:5-(pent-4-en-1-ylthio)-1-phenyl-1H-tetrazole

Chemical Property of 5-(pent-4-en-1-ylthio)-1-phenyl-1H-tetrazole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 5-(pent-4-en-1-ylthio)-1-phenyl-1H-tetrazole

There total 1 articles about 5-(pent-4-en-1-ylthio)-1-phenyl-1H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

n-Pent-4-enyl alcohol (821-09-0) + 1-Phenyl-1H-tetrazole-5-thiol (86-93-1) → 5-(pent-4-en-1-ylthio)-1-phenyl-1H-tetrazole (1019646-01-5)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 23 ℃; for 24h; Inert atmosphere;

DOI:10.1021/acs.orglett.6b00942

Reference yield: 88.0%

5-(pent-4-en-1-ylthio)-1-phenyl-1H-tetrazole (1019646-01-5) → 5-(pent-4-en-1-ylsulfonyl)-1-phenyl-1H-tetrazole (956253-12-6)

Guidance literature:

With ammonium molybdate tetrahydrate; dihydrogen peroxide; In ethanol; at 23 ℃; for 24h; Inert atmosphere;

DOI:10.1021/acs.orglett.6b00942

Reference yield: 84.0%

5-(pent-4-en-1-ylthio)-1-phenyl-1H-tetrazole (1019646-01-5) + tert-Butyl acrylate (1663-39-4,25232-27-3) → (E)-tert-butyl 6-(1-phenyl-1H-tetrazol-5-ylthio)hex-2-enoate (1006031-41-9)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; copper(l) iodide; In diethyl ether; at 35 ℃; for 3h; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/jo200360s

upstream raw materials:

n-Pent-4-enyl alcohol

1-Phenyl-1H-tetrazole-5-thiol

Downstream raw materials:

5-(pent-4-en-1-ylsulfonyl)-1-phenyl-1H-tetrazole

(E)-tert-butyl 6-(1-phenyl-1H-tetrazol-5-ylthio)hex-2-enoate