(2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol

Base Information

Chemical Name:(2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol
CAS No.:199792-06-8
Molecular Formula:C₃₄H₅₄O₇Si₂
Molecular Weight:630.97
Hs Code.:

(2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol

Synonyms:(2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol

Suppliers and Price of (2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol

There total 30 articles about (2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 199792-27-3
2-{(2S,3S,4R,4aR,6R,7S,8aR)-3,4-Bis-benzyloxy-7-(tert-butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-octahydro-pyrano[3,2-b]pyran-2-yl}-ethanol

: 199792-06-8
(2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol

: 199792-05-7
(2S,3S,4R,4aR,6R,7S,8aR)-4-Benzyloxy-7-(tert-butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3-ol

Guidance literature:: With hydrogen; palladium dihydroxide; In ethanol; ethyl acetate; for 168h; Ambient temperature;
DOI:10.1016/S0040-4039(97)10107-1

Reference yield:

: (Z)-5-{(2R,3R,4R,5S,6S)-4,5-Bis-benzyloxy-3-(4-methoxy-benzyloxy)-6-[2-(4-methoxy-benzyloxy)-ethyl]-tetrahydro-pyran-2-yl}-4-(tert-butyl-dimethyl-silanyloxy)-pent-2-enoic acid methyl ester

: 199792-06-8
(2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol

Guidance literature:: Multi-step reaction with 7 steps

1: 22 percent / DDQ / CH₂Cl₂; H₂O / 0.5 h / Ambient temperature

2: 1) NaH, 2) t-BuOK / 1) THF, room temperature, 2 h, 2) MeOH, room temperature, 18 h

3: 75 percent / TfOH / diethyl ether / 0.17 h / Ambient temperature

4: 100 percent / LiAlH₄ / diethyl ether / 0.5 h / -5 °C

5: 95 percent / NEt₃, DMAP / CH₂Cl₂ / 9 h / Ambient temperature

6: 100 percent / DDQ / CH₂Cl₂; H₂O / 0.67 h / Ambient temperature

7: 44 percent / H₂ / Pd(OH)2-C / ethanol; ethyl acetate / 168 h / 760 Torr / Ambient temperature

With dmap; lithium aluminium tetrahydride; trifluorormethanesulfonic acid; potassium tert-butylate; hydrogen; sodium hydride; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; palladium hydroxide - carbon; In diethyl ether; ethanol; dichloromethane; water; ethyl acetate;
DOI:10.1016/S0040-4020(97)10254-X

Reference yield:

: 199792-25-1
{(2R,3S,4aR,6S,7S,8R,8aR)-7,8-Bis-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-6-[2-(4-methoxy-benzyloxy)-ethyl]-octahydro-pyrano[3,2-b]pyran-2-yl}-acetic acid methyl ester

: 199792-06-8
(2S,3R,4R,4aS,6R,7S,8aR)-7-(tert-Butyl-dimethyl-silanyloxy)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2-(2-hydroxy-ethyl)-octahydro-pyrano[3,2-b]pyran-3,4-diol

Guidance literature:: Multi-step reaction with 4 steps

1: 100 percent / LiAlH₄ / diethyl ether / 0.5 h / -5 °C

2: 95 percent / NEt₃, DMAP / CH₂Cl₂ / 9 h / Ambient temperature

3: 100 percent / DDQ / CH₂Cl₂; H₂O / 0.67 h / Ambient temperature

4: 44 percent / H₂ / Pd(OH)2-C / ethanol; ethyl acetate / 168 h / 760 Torr / Ambient temperature

With dmap; lithium aluminium tetrahydride; hydrogen; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; palladium hydroxide - carbon; In diethyl ether; ethanol; dichloromethane; water; ethyl acetate;
DOI:10.1016/S0040-4020(97)10254-X