3-Biphenyl-4-YL-piperazine-1-carboxylic acid tert-butyl ester

Base Information

Chemical Name:3-Biphenyl-4-YL-piperazine-1-carboxylic acid tert-butyl ester
CAS No.:886770-41-8
Molecular Formula:C₂₁H₂₆N₂O₂
Molecular Weight:338.45
Hs Code.:2933599090
DSSTox Substance ID:DTXSID10587711
Mol file:886770-41-8.mol

Synonyms:886770-41-8;3-BIPHENYL-4-YL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;TERT-BUTYL 3-(4-PHENYLPHENYL)PIPERAZINE-1-CARBOXYLATE;tert-butyl 3-{[1,1'-biphenyl]-4-yl}piperazine-1-carboxylate;1-Piperazinecarboxylicacid, 3-[1,1'-biphenyl]-4-yl-, 1,1-dimethylethyl ester;MFCD07021283;tert-Butyl 3-([1,1'-biphenyl]-4-yl)piperazine-1-carboxylate;DTXSID10587711;1228569-38-7;1228569-50-3;AKOS005257171;AB30531;AB46822;AB46823;MCULE-7807968740;EN300-1878702;(R)-3-BIPHENYL-4-YL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(S)-3-BIPHENYL-4-YL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

Suppliers and Price of 3-Biphenyl-4-YL-piperazine-1-carboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-BIPHENYL-4-YL-PIPERAZINE-1-CARBOXYLIC ACID-TERT-BUTYL ESTER 95.00%
5MG
$ 504.94

Total 3 raw suppliers

Chemical Property of 3-Biphenyl-4-YL-piperazine-1-carboxylic acid tert-butyl ester

Chemical Property:

Vapor Pressure:3.83E-09mmHg at 25°C
Refractive Index:1.552
Boiling Point:473.8°C at 760 mmHg
Flash Point:240.3°C
PSA：41.57000
Density:1.091g/cm³
LogP:4.50170
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:338.199428076
Heavy Atom Count:25
Complexity:432

Purity/Quality:

98%min ^*data from raw suppliers

3-BIPHENYL-4-YL-PIPERAZINE-1-CARBOXYLIC ACID-TERT-BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCNC(C1)C2=CC=C(C=C2)C3=CC=CC=C3

Technology Process of 3-Biphenyl-4-YL-piperazine-1-carboxylic acid tert-butyl ester

There total 2 articles about 3-Biphenyl-4-YL-piperazine-1-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 180698-19-5
1-(1,1′-biphenyl-4-yl)piperazine

: 886770-41-8
4-(N-Boc-piperazin-3-yl)biphenyl

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 24h;

Reference yield:

: 92-91-1
biphenyl-4-acetaldehyde

: 886770-41-8
4-(N-Boc-piperazin-3-yl)biphenyl

Guidance literature:: Multi-step reaction with 3 steps

1.1: selenium(IV) oxide / tetrahydrofuran / 12 h / Reflux

2.1: ethanol / 6 h / Reflux

2.2: 4 h / 20 °C

3.1: triethylamine / dichloromethane / 24 h / 20 °C

With selenium(IV) oxide; triethylamine; In tetrahydrofuran; ethanol; dichloromethane;