3-t-butyldiphenylsilyloxy-1-{4-[(1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylcarbamoyl]-1,3-thiazol-2-yl}azetidine

Base Information

Chemical Name:3-t-butyldiphenylsilyloxy-1-{4-[(1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylcarbamoyl]-1,3-thiazol-2-yl}azetidine
CAS No.:429669-53-4
Molecular Formula:C₄₂H₅₁N₃O₃SSi₂
Molecular Weight:734.122
Hs Code.:

Synonyms:3-t-butyldiphenylsilyloxy-1-{4-[(1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylcarbamoyl]-1,3-thiazol-2-yl}azetidine

Suppliers and Price of 3-t-butyldiphenylsilyloxy-1-{4-[(1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylcarbamoyl]-1,3-thiazol-2-yl}azetidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-t-butyldiphenylsilyloxy-1-{4-[(1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylcarbamoyl]-1,3-thiazol-2-yl}azetidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-t-butyldiphenylsilyloxy-1-{4-[(1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylcarbamoyl]-1,3-thiazol-2-yl}azetidine

There total 4 articles about 3-t-butyldiphenylsilyloxy-1-{4-[(1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylcarbamoyl]-1,3-thiazol-2-yl}azetidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 429666-50-2
3-t-butyldiphenylsilyloxy-1-(4-ethoxycarbonyl-1,3-thiazol-2-yl)azetidine

: (1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylamine-trimethylaluminium

: 429669-53-4
3-t-butyldiphenylsilyloxy-1-{4-[(1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylcarbamoyl]-1,3-thiazol-2-yl}azetidine

Guidance literature:: 3-t-butyldiphenylsilyloxy-1-(4-ethoxycarbonyl-1,3-thiazol-2-yl)azetidine; (1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylamine-trimethylaluminium; In benzene; at 20 ℃; Heating / reflux;

With acetic acid; In water; ethyl acetate; benzene; at 0 - 20 ℃; for 1h;

With sodium hydrogencarbonate; In water; ethyl acetate; benzene;

Reference yield:

: 429666-50-2
3-t-butyldiphenylsilyloxy-1-(4-ethoxycarbonyl-1,3-thiazol-2-yl)azetidine

: 429669-51-2
[(1S)-2-(t-butyldiphenylsilyloxy)-1-methyl-ethyl]carbamic acid benzyl ester

: (1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylamine-trimethylaluminium

: 429669-53-4
3-t-butyldiphenylsilyloxy-1-{4-[(1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylcarbamoyl]-1,3-thiazol-2-yl}azetidine

Guidance literature:: With acetic acid; In methanol; palladium on charcoal; ethyl acetate; benzene;

Reference yield:

: 429666-44-4
1-(4-ethoxycarbonyl-1,3-thiazol-2-yl)-3-hydroxyazetidine

: 429669-53-4
3-t-butyldiphenylsilyloxy-1-{4-[(1S)-2-(t-butyldiphenylsilyloxy)-1-methylethylcarbamoyl]-1,3-thiazol-2-yl}azetidine

Guidance literature:: Multi-step reaction with 2 steps

1: N-methyl-acetamide; ethanol

2: acetic acid / methanol; palladium on charcoal; ethyl acetate; benzene

With acetic acid; In N-methyl-acetamide; methanol; palladium on charcoal; ethanol; ethyl acetate; benzene;