(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid

Base Information

• Chemical Name: (5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid
• CAS No.: 247042-78-0
• Molecular Formula: C₃₁H₃₅NO₆
• Molecular Weight: 517.622

Synonyms:(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid

Chemical Property of (5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid

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Technology Process of (5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid

There total 2 articles about (5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-benzo[1,3]dioxol-5-yl-2-butyl-7-{2-[3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-propyl]-4-methoxy-phenyl}-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid tert-butyl ester (258349-59-6) → (5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid (247042-78-0)

Guidance literature:

With hydrogenchloride; at 20 - 25 ℃;

DOI:10.1021/jo991292t

Reference yield:

(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid; compound with benzylamine → (5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid (247042-78-0)

Guidance literature:

With hydrogenchloride; In water; pH=3 - 4;

DOI:10.1021/jo991292t

Reference yield:

(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid (247042-78-0) → J 104132 (198279-45-7,224448-58-2)

Guidance literature:

With chromium(VI) oxide; periodic acid; In water; at -3 - 0 ℃;

DOI:10.1021/jo991292t

upstream raw materials:

5-benzo[1,3]dioxol-5-yl-2-butyl-7-{2-[3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-propyl]-4-methoxy-phenyl}-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid tert-butyl ester

Downstream raw materials:

J 104132

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