2-(3-Benzoylphenyl)propionitrile, (R)-

Base Information

Chemical Name:2-(3-Benzoylphenyl)propionitrile, (R)-
CAS No.:161527-65-7
Molecular Formula:C₁₆H₁₃NO
Molecular Weight:235.285
Hs Code.:
UNII:PML7ZTD77M
Nikkaji Number:J1.511.805I
Wikidata:Q27286637

Synonyms:PML7ZTD77M;UNII-PML7ZTD77M;2-(3-Benzoylphenyl)propionitrile, (R)-;(R)-2-(3-Benzoylphenyl)propionitrile;161527-65-7;Benzeneacetonitrile, 3-benzoyl-alpha-methyl-, (R)-;Q27286637;BENZENEACETONITRILE, 3-BENZOYL-.ALPHA.-METHYL-, (R)-

Suppliers and Price of 2-(3-Benzoylphenyl)propionitrile, (R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(3-Benzoylphenyl)propionitrile, (R)-

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:235.099714038
Heavy Atom Count:18
Complexity:334

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C#N)C1=CC(=CC=C1)C(=O)C2=CC=CC=C2
Isomeric SMILES:C[C@@H](C#N)C1=CC(=CC=C1)C(=O)C2=CC=CC=C2

Technology Process of 2-(3-Benzoylphenyl)propionitrile, (R)-

There total 5 articles about 2-(3-Benzoylphenyl)propionitrile, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 42872-30-0
alpha-(m-benzoylphenyl)propionitrile

: (2R)-2-[3-(phenylcarbonyl)phenyl]propanamide

: 162681-69-8
(S)-2-(3-benzoylphenyl)propanamide

: 1421692-22-9
(S)-2-(3-benzoylphenyl)propanenitrile

: 161527-65-7
(2R)-[3-(phenylcarbonyl)phenyl]propanenitrile

: 22161-81-5,22161-86-0
S-ketoprofen

Guidance literature:: With Rhodococcus erythropolis SET₁ cells; In aq. phosphate buffer; at 25 ℃; pH=7; enantioselective reaction; Microbiological reaction;
DOI:10.1002/ejoc.201403201

Reference yield:

: (2R)-2-[3-(phenylcarbonyl)phenyl]propanamide

: 161527-65-7
(2R)-[3-(phenylcarbonyl)phenyl]propanenitrile

Guidance literature:: (2R)-2-[3-(phenylcarbonyl)phenyl]propanamide; With triethylamine; In dichloromethane; at 0 ℃; for 0.25h; Inert atmosphere;

With trifluoroacetyl chloride; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.tetlet.2013.09.022

Reference yield:

: 1421692-00-3
(3-(1-(tert-butyldimethylsilylimino)prop-1-en-2-yl)phenyl)(phenyl)methanone

: 1421692-22-9
(S)-2-(3-benzoylphenyl)propanenitrile

: 161527-65-7
(2R)-[3-(phenylcarbonyl)phenyl]propanenitrile

Guidance literature:: With (S)-3,3'-bis(2,4,6-tri-iso-propylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; In methanol; toluene; pentane; at -78 - 20 ℃; for 12h; Overall yield = 92 %; Overall yield = 41 mg; enantioselective reaction;
DOI:10.1021/ja312141b