2,6-Difluoro-4-methoxyphenylacetic acid

Base Information

Chemical Name:2,6-Difluoro-4-methoxyphenylacetic acid
CAS No.:886498-98-2
Molecular Formula:C9H8F2O3
Molecular Weight:202.158
Hs Code.:2918990090
DSSTox Substance ID:DTXSID90409280
Wikidata:Q72463331
Mol file:886498-98-2.mol

Synonyms:2,6-Difluoro-4-methoxyphenylacetic acid;886498-98-2;2-(2,6-difluoro-4-methoxyphenyl)acetic acid;MFCD04115927;2-(2,6-Difluoro-4-methoxyphenyl)aceticacid;2,6-difluoro-4-methoxyphenylaceticacid;2-(2,6-difluoro-4-methoxy-phenyl)acetic Acid;(2,6-difluoro-4-methoxyphenyl)acetic acid;2,6-DIFLUORO-4-METHOXYBENZENEACETIC ACID;SCHEMBL1462161;DTXSID90409280;KXWRAINJKJTUDG-UHFFFAOYSA-N;CL8751;AKOS015853408;AB20640;AM84023;DS-10886;FT-0648756;(2,6-Difluoro-4-methoxy-phenyl)-acetic acid;2 pound not6-Difluoro-4-methoxyphenylacetic acid;J-507472

Suppliers and Price of 2,6-Difluoro-4-methoxyphenylacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,6-Difluoro-4-methoxyphenylaceticAcid
500mg
$ 130.00

Matrix Scientific
2,6-Difluoro-4-methoxyphenylacetic acid 95+%
1g
$ 153.00

Matrix Scientific
2,6-Difluoro-4-methoxyphenylacetic acid 95+%
5g
$ 457.00

Crysdot
2,6-Difluoro-4-methoxyphenylaceticacid 97%
5g
$ 248.00

Chemenu
2,6-Difluoro-4-methoxyphenylaceticacid 95+%
5g
$ 234.00

Ambeed
2,6-Difluoro-4-methoxyphenylaceticacid 98%
5g
$ 217.00

AK Scientific
2,6-Difluoro-4-methoxyphenylaceticacid
1g
$ 156.00

Abosyn
2,6-Difluoro-4-methoxyphenylaceticacid 95-98%
1g
$ 370.00

Total 34 raw suppliers

Chemical Property of 2,6-Difluoro-4-methoxyphenylacetic acid

Chemical Property:

Melting Point:138-141℃
Boiling Point:269.4 °C at 760 mmHg
Flash Point:116.7 °C
PSA：46.53000
Density:1.354 g/cm³
LogP:1.60050
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:202.04415044
Heavy Atom Count:14
Complexity:198

Purity/Quality:

97% ^*data from raw suppliers

2,6-Difluoro-4-methoxyphenylaceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C(=C1)F)CC(=O)O)F

Technology Process of 2,6-Difluoro-4-methoxyphenylacetic acid

There total 3 articles about 2,6-Difluoro-4-methoxyphenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1268822-63-4
2-(2,6-difluoro-4-methoxyphenyl)malonic acid

: 886498-98-2
2-(2,6-difluoro-4-methoxyphenyl)acetic acid

Guidance literature:: at 160 ℃;

Reference yield:

: 244092-40-8
diethyl 2-(2,6-difluoro-4-methoxyphenyl)malonate

: 886498-98-2
2-(2,6-difluoro-4-methoxyphenyl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; water / diethyl ether / Heating; Reflux

2: 160 °C

With water; sodium hydroxide; In diethyl ether;

Reference yield:

: diethyl 2-(2,6-difluoro-4-methoxyphenyl)malonate

: 886498-98-2
2-(2,6-difluoro-4-methoxyphenyl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / water; diethyl ether / Reflux

2: 160 °C

With sodium hydroxide; In diethyl ether; water;
DOI:10.1002/cmdc.201300015