(S)-3,5-difluoro-4-formylphenyl 2-(acetoxymethyl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:(S)-3,5-difluoro-4-formylphenyl 2-(acetoxymethyl)pyrrolidine-1-carboxylate
CAS No.:1296131-21-9
Molecular Formula:C₁₅H₁₅F₂NO₅
Molecular Weight:327.285
Hs Code.:

Synonyms:(S)-3,5-difluoro-4-formylphenyl 2-(acetoxymethyl)pyrrolidine-1-carboxylate

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Chemical Property of (S)-3,5-difluoro-4-formylphenyl 2-(acetoxymethyl)pyrrolidine-1-carboxylate

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Technology Process of (S)-3,5-difluoro-4-formylphenyl 2-(acetoxymethyl)pyrrolidine-1-carboxylate

There total 2 articles about (S)-3,5-difluoro-4-formylphenyl 2-(acetoxymethyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 1296132-58-5
(S)-(1-(chlorocarbonyl)pyrrolidin-2-yl)methyl acetate

: 532967-21-8
2,6-difluoro-4-hydroxybenzaldehyde

: 1296131-21-9
(S)-3,5-difluoro-4-formylphenyl 2-(acetoxymethyl)pyrrolidine-1-carboxylate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 48h;

Reference yield:

: (-)-(2S)-(1-benzylpyrrolidin-2-yl)methyl acetate

: 1296131-21-9
(S)-3,5-difluoro-4-formylphenyl 2-(acetoxymethyl)pyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 20 °C / Cooling with acetone-dry ice

2: triethylamine / dichloromethane / 48 h / 20 °C

With triethylamine; In dichloromethane;