(-)-ethyl (2'R,5'S,6'R)-2-[4'-benzyl-5'-(tert-butyldimethylsilyloxymethyl)-1'-(2-ethoxycarbonylallyl)-6'-(1-naphthyl)-3'-oxopiperazin-2'-yl]methylacrylate

Base Information

Chemical Name:(-)-ethyl (2'R,5'S,6'R)-2-[4'-benzyl-5'-(tert-butyldimethylsilyloxymethyl)-1'-(2-ethoxycarbonylallyl)-6'-(1-naphthyl)-3'-oxopiperazin-2'-yl]methylacrylate
CAS No.:1099822-20-4
Molecular Formula:C₄₀H₅₂N₂O₆Si
Molecular Weight:684.948
Hs Code.:

Synonyms:(-)-ethyl (2'R,5'S,6'R)-2-[4'-benzyl-5'-(tert-butyldimethylsilyloxymethyl)-1'-(2-ethoxycarbonylallyl)-6'-(1-naphthyl)-3'-oxopiperazin-2'-yl]methylacrylate

Suppliers and Price of (-)-ethyl (2'R,5'S,6'R)-2-[4'-benzyl-5'-(tert-butyldimethylsilyloxymethyl)-1'-(2-ethoxycarbonylallyl)-6'-(1-naphthyl)-3'-oxopiperazin-2'-yl]methylacrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-ethyl (2'R,5'S,6'R)-2-[4'-benzyl-5'-(tert-butyldimethylsilyloxymethyl)-1'-(2-ethoxycarbonylallyl)-6'-(1-naphthyl)-3'-oxopiperazin-2'-yl]methylacrylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-ethyl (2'R,5'S,6'R)-2-[4'-benzyl-5'-(tert-butyldimethylsilyloxymethyl)-1'-(2-ethoxycarbonylallyl)-6'-(1-naphthyl)-3'-oxopiperazin-2'-yl]methylacrylate

There total 1 articles about (-)-ethyl (2'R,5'S,6'R)-2-[4'-benzyl-5'-(tert-butyldimethylsilyloxymethyl)-1'-(2-ethoxycarbonylallyl)-6'-(1-naphthyl)-3'-oxopiperazin-2'-yl]methylacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 878557-00-7
(+)-(5R,6S)-1-benzyl-6-(t-butyldimethylsilyloxymethyl)-5-(1-naphthyl)-5,6-dihydro-1H-pyrazin-2-one

: 17435-72-2
ethyl 2-bromomethyl-2-propenoate

: 1099822-21-5
(+)-(3S,4R,8aR)-2-benzyl-3-(tert-butyldimethylsilyloxymethyl)-7-methylene-4-(1-naphthyl)tetrahydropyrrolo[1,2-a]pyrazin-1,6-dione

: 1099822-20-4
(-)-ethyl (2'R,5'S,6'R)-2-[4'-benzyl-5'-(tert-butyldimethylsilyloxymethyl)-1'-(2-ethoxycarbonylallyl)-6'-(1-naphthyl)-3'-oxopiperazin-2'-yl]methylacrylate

Guidance literature:: With chloro-trimethyl-silane; zinc; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 64h; diastereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2008.10.034