(5Z)-(9S,11R,15R)-11,15-bis(tetrahydropyran-2-yloxy)-15-cyclohexyl-2,3,4,16,17,18,19,20-octanor-9-hydroxy-5-prostenol

Base Information

Chemical Name:(5Z)-(9S,11R,15R)-11,15-bis(tetrahydropyran-2-yloxy)-15-cyclohexyl-2,3,4,16,17,18,19,20-octanor-9-hydroxy-5-prostenol
CAS No.:467253-89-0
Molecular Formula:C₂₈H₄₈O₆
Molecular Weight:480.686
Hs Code.:

Synonyms:(5Z)-(9S,11R,15R)-11,15-bis(tetrahydropyran-2-yloxy)-15-cyclohexyl-2,3,4,16,17,18,19,20-octanor-9-hydroxy-5-prostenol

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Chemical Property of (5Z)-(9S,11R,15R)-11,15-bis(tetrahydropyran-2-yloxy)-15-cyclohexyl-2,3,4,16,17,18,19,20-octanor-9-hydroxy-5-prostenol

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Technology Process of (5Z)-(9S,11R,15R)-11,15-bis(tetrahydropyran-2-yloxy)-15-cyclohexyl-2,3,4,16,17,18,19,20-octanor-9-hydroxy-5-prostenol

There total 1 articles about (5Z)-(9S,11R,15R)-11,15-bis(tetrahydropyran-2-yloxy)-15-cyclohexyl-2,3,4,16,17,18,19,20-octanor-9-hydroxy-5-prostenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 170290-75-2
(5Z)-(9S,11R,15R)-11,15-bis(tetrahydropyran-2-yloxy)-15-cyclohexyl-2,3,4,16,17,18,19,20-octanor-9-(triethylsiloxy)-5-prostenol

: 467253-89-0
(5Z)-(9S,11R,15R)-11,15-bis(tetrahydropyran-2-yloxy)-15-cyclohexyl-2,3,4,16,17,18,19,20-octanor-9-hydroxy-5-prostenol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 1h;
DOI:10.1016/S0968-0896(02)00016-0

Reference yield: 86.0%

: 5292-43-3
bromoacetic acid tert-butyl ester

: 467253-89-0
(5Z)-(9S,11R,15R)-11,15-bis(tetrahydropyran-2-yloxy)-15-cyclohexyl-2,3,4,16,17,18,19,20-octanor-9-hydroxy-5-prostenol

: 170290-77-4
(5Z)-(9S,11R,15R)-11,15-bis(tetrahydropyran-2-yloxy)-15-cyclohexyl-9-hydroxy-3-oxa-16,17,18,19,20-pentanor-5-prostenoic acid t-butyl ester

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In water; toluene; for 0.666667h;
DOI:10.1016/S0968-0896(02)00016-0