2-<2-(4-aminophenyl)-6-benzimidazoyl>-6-(1-methyl-4-piperazinyl)benzimidazole

Base Information

Chemical Name:2-<2-(4-aminophenyl)-6-benzimidazoyl>-6-(1-methyl-4-piperazinyl)benzimidazole
CAS No.:23476-82-6
Molecular Formula:C₂₅H₂₅N₇
Molecular Weight:423.52
Hs Code.:

Synonyms:2-<2-(4-aminophenyl)-6-benzimidazoyl>-6-(1-methyl-4-piperazinyl)benzimidazole

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Chemical Property of 2-<2-(4-aminophenyl)-6-benzimidazoyl>-6-(1-methyl-4-piperazinyl)benzimidazole

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Technology Process of 2-<2-(4-aminophenyl)-6-benzimidazoyl>-6-(1-methyl-4-piperazinyl)benzimidazole

There total 4 articles about 2-<2-(4-aminophenyl)-6-benzimidazoyl>-6-(1-methyl-4-piperazinyl)benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 23555-02-4
4-nitro-1-<5'-<5''-(4'''-methylpiperazin-1'''-yl)benzimidazol-2''-yl>benzimidazol-2'-yl>benzene

: 23476-82-6
2-<2-(4-aminophenyl)-6-benzimidazoyl>-6-(1-methyl-4-piperazinyl)benzimidazole

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 2h; under 760 Torr;
DOI:10.1021/ja960948m

Reference yield:

: 23491-49-8
2-amino-4-<5'-(4''-methylpiperazin-1''-yl)benzimidazol-2'-yl>aniline

: 23476-82-6
2-<2-(4-aminophenyl)-6-benzimidazoyl>-6-(1-methyl-4-piperazinyl)benzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / AcOH / methanol / 2 h / Heating

2: 83 percent / H₂ / Pd/C / methanol / 2 h / 760 Torr

With hydrogen; acetic acid; palladium on activated charcoal; In methanol;
DOI:10.1021/ja960948m

Reference yield:

: 52708-02-8
4-nitrobenzimidic acid methyl ester

: 23476-82-6
2-<2-(4-aminophenyl)-6-benzimidazoyl>-6-(1-methyl-4-piperazinyl)benzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / AcOH / methanol / 2 h / Heating

2: 83 percent / H₂ / Pd/C / methanol / 2 h / 760 Torr

With hydrogen; acetic acid; palladium on activated charcoal; In methanol;
DOI:10.1021/ja960948m