2-N-BOC-2-AMINOMETHYL-3-(3-CHLORO-PHENYL)-PROPIONIC ACID

Base Information

• Chemical Name: 2-N-BOC-2-AMINOMETHYL-3-(3-CHLORO-PHENYL)-PROPIONIC ACID
• CAS No.: 886364-85-8
• Molecular Formula: C15H20 Cl N O4
• Molecular Weight: 313.781
• Mol file: 886364-85-8.mol

Synonyms:2-N-Boc-2-aminomethyl-3-(3-chloro-phenyl);2-N-Boc-2-aminomethyl-3-(3-chloro-phenyl)-propionic acid;2-[(3-chlorophenyl)methyl]-3-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoic acid;

Chemical Property of 2-N-BOC-2-AMINOMETHYL-3-(3-CHLORO-PHENYL)-PROPIONIC ACID

Chemical Property:

• Vapor Pressure: 1.68E-09mmHg at 25°C
• Refractive Index: 1.534
• Boiling Point: 466.5°C at 760 mmHg
• Flash Point: 235.9°C
• PSA: 75.63000
• Density: 1.22g/cm³
• LogP: 3.49890

Purity/Quality:

97% ^*data from raw suppliers

2-(TERT-BUTOXYCARBONYLAMINO-METHYL)-3-(3-CHLORO-PHENYL)-PROPIONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-N-BOC-2-AMINOMETHYL-3-(3-CHLORO-PHENYL)-PROPIONIC ACID

There total 1 articles about 2-N-BOC-2-AMINOMETHYL-3-(3-CHLORO-PHENYL)-PROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2E)-2-{[(tert-butoxycarbonyl)amino]methyl}-3-(3-chlorophenyl)-2-propenoic acid (889855-65-6) → N-(tert-butoxycarbonyl)-2-(3-chlorobenzyl)-β-alanine (886364-85-8)

Guidance literature:

With hydrogen; platinum(IV) oxide; In methanol; at 20 ℃; for 0.75h;

Reference yield:

N-(tert-butoxycarbonyl)-2-(3-chlorobenzyl)-β-alanine (886364-85-8) + p-nitrobenzenesulfonamide (6325-93-5) → tert-butyl 2-(3-chlorobenzyl)-3-{[(4-nitrophenyl)sulfonyl]amino}-3-oxopropylcarbamate (889857-52-7)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 17h;

upstream raw materials:

(2E)-2-{[(tert-butoxycarbonyl)amino]methyl}-3-(3-chlorophenyl)-2-propenoic acid

Downstream raw materials:

tert-butyl 2-(3-chlorobenzyl)-3-{[(4-nitrophenyl)sulfonyl]amino}-3-oxopropylcarbamate