3,5-bis(diphenylphosphinoylmethyl)trimethylsilylethynylbenzene

Base Information

• Chemical Name: 3,5-bis(diphenylphosphinoylmethyl)trimethylsilylethynylbenzene
• CAS No.: 263353-18-0
• Molecular Formula: C₃₇H₃₆O₂P₂Si
• Molecular Weight: 602.725
• Mol file: 263353-18-0.mol

Synonyms:3,5-bis(diphenylphosphinoylmethyl)trimethylsilylethynylbenzene

Chemical Property of 3,5-bis(diphenylphosphinoylmethyl)trimethylsilylethynylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-bis(diphenylphosphinoylmethyl)trimethylsilylethynylbenzene

There total 3 articles about 3,5-bis(diphenylphosphinoylmethyl)trimethylsilylethynylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3,5-bis(diphenylphosphinoylmethyl)iodobenzene (263353-14-6) + trimethylsilylacetylene (1066-54-2) → 3,5-bis(diphenylphosphinoylmethyl)trimethylsilylethynylbenzene (263353-18-0)

Guidance literature:

bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In various solvent(s); at 80 ℃; for 3h;

DOI:10.1023/B:RUJO.0000010214.72250.5a

Reference yield: 95.0%

1,3-Bis-(diphenyl-phosphinoylmethyl)-5-iodo-benzene; compound with benzene + trimethylsilylacetylene (1066-54-2) → 3,5-bis(diphenylphosphinoylmethyl)trimethylsilylethynylbenzene (263353-18-0)

Guidance literature:

With piperidine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; at 80 ℃; for 3h;

DOI:10.1016/S0040-4039(99)02181-4

Reference yield:

Ethyl diphenylphosphinite (719-80-2) → 3,5-bis(diphenylphosphinoylmethyl)trimethylsilylethynylbenzene (263353-18-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / m-xylene / 1 h / 130 °C

2: 95 percent / Pd(PPh₃)2Cl₂; CuI / various solvent(s) / 3 h / 80 °C

bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In m-xylene; 1: Arbuzov reaction / 2: Sonogashira reaction;

DOI:10.1023/B:RUJO.0000010214.72250.5a

upstream raw materials:

trimethylsilylacetylene

3,5-bis(diphenylphosphinoylmethyl)iodobenzene

Ethyl diphenylphosphinite

Downstream raw materials:

1,4-bis[3,5-bis(diphenylphosphinoylmethyl)phenyl]butadiyne

3,3',5,5'-tetrakis(diphenylphosphinoylmethyl)diphenylacetylene

3,5-bis[(diphenylphosphinoxide)methyl]phenylacetylene